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MINA / MINA53

MYC induced nuclear antigen

Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles.

Gene Name:	MYC induced nuclear antigen
Synonyms:	MINA, MYC-induced nuclear antigen, NO52, MINA53, MYC induced nuclear antigen, MDIG, Nucleolar protein 52
Target Sequences:	NM_032778 NP_116167.3 Q8IUF8

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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