MIEF1 / SMCR7L

mitochondrial elongation factor 1

Mitochondrial outer membrane protein which regulates mitochondrial fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface independently of the mitochondrial fission FIS1 and MFF proteins. Regulates DNM1L GTPase activity and DNM1L oligomerization. Binds ADP and can also bind GDP, although with lower affinity. Does not bind CDP, UDP, ATP, AMP or GTP. Inhibits DNM1L GTPase activity in the absence of bound ADP. Requires ADP to stimulate DNM1L GTPase activity and the assembly of DNM1L into long, oligomeric tubules with a spiral pattern, as opposed to the ring-like DNM1L oligomers observed in the absence of bound ADP. Does not require ADP for its function in recruiting DNM1L.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

MIEF1 / SMCR7L (3)

Publications

No (3)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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Human MIEF1 / SMCR7L Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71987

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.1 kDa

Price:

20 µg/$1,107

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Human MIEF1 / SMCR7L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G91102

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.1 kDa

Price:

20 µg/$150

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MIEF1 / SMCR7L Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111527

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.1 kDa

Price:

100 µg/$494

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