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MICB

MHC class I polypeptide-related sequence B

MICB is a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules; however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.

Gene Name: MHC class I polypeptide-related sequence B
Synonyms: MICB, MHC class I mic-B antigen, MIC-B, PERB11.2
Target Sequences: NM_005931 NP_005922.2 Q29980

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
MICB (7)
No (7)
Fc-His, C-terminus (1)
GST (1)
GST, N-terminus (1)
His,C-terminus (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (3)
Low endotoxin level (2)
MICB Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MICB Protein - Purified recombinant protein MICB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
42.4 kDa
20 µg/$1,107
MICB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
42.4 kDa
20 µg/$150
MICB Protein - 12.5% SDS-PAGE of human MICB stained with Coomassie Blue
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Wheat Germ Extract
GST
64 kDa
2 µg/$439
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HEK 293 Cells
Fc-His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
59.5 kDa
100 µg/$721
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
33 kDa
100 µg/$721
MICB Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
42.4 kDa
100 µg/$494
Viewing 1-7 of 7 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).