MICA

MHC class I polypeptide-related sequence A

MICA is the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.

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Products

Proteins (14)

Type

Over-Expression Lysate (4)

Recombinant (10)

Target

MICA (14)

Publications

No (14)

Tag

6His, C-terminus (2)

Fc, C-terminus (3)

GST (1)

His (2)

Myc-DDK (Flag) (6)

Species

Human (12)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (4)

Human Cells (3)

Mammalian Cells (3)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (6)

Biologically Active

Biologically active (1)

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Human MICA Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66283

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.3 kDa

Price:

20 µg/$1,107

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Human MICA Protein (Recombinant 6His, C-terminus) (Glu24-Gln308) - LS-G38996

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

33.87kD

Price:

10 µg/$262; 50 µg/$372; 500 µg/$1,348; 1 mg/$1,716

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MICA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129637

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.3 kDa

Price:

100 µg/$494

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Human MICA Protein (Recombinant GST) (Full Length) - LS-G29334

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

69.3 kDa

Price:

10 µg/$479; 25 µg/$670

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Human MICA Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66282

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.7 kDa

Price:

20 µg/$1,107

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Human MICA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77353

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.95 kDa

Price:

20 µg/$150

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Human MICA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77354

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.3 kDa

Price:

20 µg/$150

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MICA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G98980

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.95 kDa

Price:

100 µg/$494

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Human MICA Protein (Recombinant His) (Met1-Gln308) - LS-G97694

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

34 kDa

Price:

100 µg/$721

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Human MICA Protein (Recombinant His) - LS-G3268

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$954; 10 µg/$292; 20 µg/$361; 100 µg/$544; 500 µg/$1,447

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Human MICA Protein (Recombinant Fc, C-terminus) (Ala23-Glu308) - LS-G39709

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

59.9kD

Price:

10 µg/$281; 50 µg/$395; 500 µg/$1,585; 1 mg/$2,157

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Human MICA Protein (Recombinant Fc, C-terminus) - LS-G136803

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

59.9 kDa

Price:

50 µg/$453; 10 µg/$303; 1 mg/$2,837; 500 µg/$1,987

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Human MICA Protein (Recombinant 6His, C-terminus) (Glu24-Gln308) - LS-G138979

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

33.9 kDa

Price:

10 µg/$262; 50 µg/$368

Select

Human MICA Protein (Recombinant Fc, C-terminus) (Ala23-Glu308) - LS-G139115

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

59.9 kDa

Price:

10 µg/$281; 50 µg/$389

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