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MFNG / Manic Fringe

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

MFNG / Manic Fringe is a member of the fringe gene family which also includes radical and lunatic fringe genes. They all encode evolutionarily conserved secreted proteins that act in the Notch receptor pathway to demarcate boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling.

Gene Name: MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Synonyms: MFNG, Manic fringe
Target Sequences: NM_002405 NP_002396.2 O00587

☰ Filters
Products
Proteins (9)
Over-Expression Lysate (4)
Recombinant (5)
MFNG / Manic Fringe (9)
No (9)
GST (1)
GST, N-terminus (1)
His-T7 (3)
Myc-DDK (Flag) (4)
Human (5)
Mouse (1)
Rat (1)
293T Cells (2)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
MFNG / Manic Fringe Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
35.1 kDa
100 µg/$494
MFNG / Manic Fringe Protein - 12.5% SDS-PAGE of human MFNG stained with Coomassie Blue
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Wheat Germ Extract
GST
62.6 kDa
10 µg/$479; 25 µg/$670
MFNG / Manic Fringe Protein - Recombinant  Beta-1,3-N-Acetylglucosaminyltransferase Manic Fringe By SDS-PAGE
Select
E. coli
His-T7
30.6 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
MFNG / Manic Fringe Protein - Recombinant  Beta-1,3-N-Acetylglucosaminyltransferase Manic Fringe By SDS-PAGE
Select
E. coli
His-T7
32.5 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
MFNG / Manic Fringe Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MFNG / Manic Fringe Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
35.1 kDa
20 µg/$150
MFNG / Manic Fringe Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
36 kDa
20 µg/$150
MFNG / Manic Fringe Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
36 kDa
100 µg/$494
MFNG / Manic Fringe Protein - Recombinant Beta-1,3-N-Acetylglucosaminyltransferase Manic Fringe By SDS-PAGE
Select
E. coli
His-T7
30.6 kDa
10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).