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MEX3C

mex-3 RNA binding family member C

E3 ubiquitin ligase responsible for the post-transcriptional regulation of common HLA-A allotypes. Binds to the 3' UTR of HLA-A2 mRNA, and regulates its levels by promoting mRNA decay. RNA binding is sufficient to prevent translation, but ubiquitin ligase activity is required for mRNA degradation.

Gene Name: mex-3 RNA binding family member C
Synonyms: MEX3C, RNF194, RING finger protein 194, RNA-binding protein MEX3C, BM-013, Mex-3 homolog C (C. elegans), MEX-3C, RKHD2
Target Sequences: NM_016626 NP_057710.3 Q5U5Q3

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Proteins (1)
Recombinant (1)
MEX3C (1)
No (1)
GST (1)
Human (1)
Wheat Germ Extract (1)
Purified (1)
MEX3C Protein - 12.5% SDS-PAGE of human MEX3C stained with Coomassie Blue
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Wheat Germ Extract
GST
77.99 kDa
10 µg/$479; 25 µg/$670
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).