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METTL3

methyltransferase like 3

N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing. M6A regulates the length of the ciracadian clock: acts as a early pace-setter in the circadian loop by putting mRNA production on a fast-track for facilitating nuclear processing, thereby providing an early point of control in setting the dynamics of the feedback loop.

Gene Name: methyltransferase like 3
Synonyms: METTL3, M6A, Methyltransferase like 3, MTA70, Spo8, IME4, MRNA m(6)A methyltransferase, MT-A70
Target Sequences: AF014837 AAB71850.1 Q86U44

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
METTL3 (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
METTL3 Protein - 12.5% SDS-PAGE of human METTL3 stained with Coomassie Blue
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Wheat Germ Extract
GST
90.9 kDa
10 µg/$479; 25 µg/$670
METTL3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
64.3 kDa
100 µg/$494
METTL3 Protein - Purified recombinant protein METTL3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
64.3 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
64.3 kDa
20 µg/$150
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).