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METTL3

methyltransferase like 3

N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing. M6A regulates the length of the ciracadian clock: acts as a early pace-setter in the circadian loop by putting mRNA production on a fast-track for facilitating nuclear processing, thereby providing an early point of control in setting the dynamics of the feedback loop.

Gene Name: methyltransferase like 3
Synonyms: METTL3, M6A, Methyltransferase like 3, MTA70, Spo8, IME4, MRNA m(6)A methyltransferase, MT-A70
Target Sequences: AF014837 AAB71850.1 Q86U44

☰ Filters
Products
Antibodies (28)
Primary (28)
METTL3 (28)
Human (28)
Mouse (21)
Rat (16)
Bat (12)
Bovine (12)
Chimpanzee (12)
Dog (12)
Gibbon (12)
Goat (6)
Guinea pig (12)
Hamster (12)
Horse (12)
Monkey (12)
Pig (9)
Rabbit (12)
Xenopus (6)
Zebrafish (12)
IHC (11)
IHC-P (8)
WB (26)
ELISA (3)
IP (5)
Peptide-ELISA (1)
rabbit (26)
mouse (2)
Product Group
IHCPlus (2)
IgG (21)
IgG1 (2)
monoclonal mc (2)
polyclonal pc (26)
OTI1B7 (2)
Biotin Conjugated (4)
Carrier-free (1)
FITC Conjugated (4)
HRP Conjugated (4)
Unconjugated (16)
C-Terminus (4)
N-Terminus (4)
aa206-255 (4)
aa503-552 (4)
aa1-284 (2)
aa1-50 (2)
aa530-580 (1)
No (28)
METTL3 Antibody - Detection of Human METTL3/MT-A70 by Immunohistochemistry. Sample: FFPE section of human prostate carcinoma. Antibody: Affinity purified rabbit anti-METTL3/MT-A70 used at a dilution of 1:1000 (0.2 ug/ml). Detection: DAB.
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METTL3 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC, IHC-P, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
METTL3 Antibody - Immunohistochemical analysis of METTL3 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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METTL3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
METTL3 Antibody - METTL3 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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METTL3 Rabbit anti-Human Polyclonal (aa503-552) Antibody
Human
WB
Unconjugated
100 µl/$424
METTL3 Antibody - METTL3 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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METTL3 Rabbit anti-Human Polyclonal (aa503-552) (HRP) Antibody
Xenopus, Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Pig, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
METTL3 Antibody - METTL3 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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METTL3 Rabbit anti-Human Polyclonal (aa503-552) (Biotin) Antibody
Xenopus, Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Pig, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
METTL3 Antibody - METTL3 antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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METTL3 Rabbit anti-Human Polyclonal (aa503-552) (FITC) Antibody
Xenopus, Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Pig, Horse, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
METTL3 Antibody - Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE)
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METTL3 Rabbit anti-Human Polyclonal (aa530-580) Antibody
Human
IHC, IHC-P, IP
Unconjugated
50 µl/$460
METTL3 Antibody - Human Colon, Lymphoid Aggregate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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METTL3 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Human
IHC, IHC-P
Unconjugated
50 µl/$460
METTL3 Antibody - Immunohistochemistry of paraffin-embedded human lung cancer tissue.
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METTL3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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METTL3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
METTL3 Antibody - METTL3 antibody ARP39390_T100-NP_062826-METTL3 (methyltransferase like 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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METTL3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$397
METTL3 Antibody - METTL3 antibody ARP39390_T100-NP_062826-METTL3 (methyltransferase like 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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METTL3 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$442
METTL3 Antibody - METTL3 antibody ARP39390_T100-NP_062826-METTL3 (methyltransferase like 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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METTL3 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$442
METTL3 Antibody - METTL3 antibody ARP39390_T100-NP_062826-METTL3 (methyltransferase like 3) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human intestine.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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METTL3 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Zebrafish, Rat, Hamster, Rabbit, Mouse, Dog, Guinea pig, Bovine, Horse, Bat, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$442
METTL3 Antibody - 1:100 staining human lung carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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METTL3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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METTL3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$331
METTL3 Antibody - Western blot testing of human 1) placenta, 2) HepG2, 3) K562, 4) HeLa and 5) Caco-2 lysate with METTL3 antibody at 0.5ug/ml. Expected molecular weight: 64-70 kDa.
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METTL3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$575
METTL3 Antibody - ICC analysis of METTL3 using anti-METTL3 antibody. METTL3 was detected in immunocytochemical section of A549 cell. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-METTL3 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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METTL3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
10 µg/$318; 100 µg/$470
METTL3 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY METTL3. (Right lane) cDNA for 48 hrs and lysed
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METTL3 Mouse anti-Human Monoclonal (aa1-284) (OTI1B7) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$434
METTL3 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY METTL3. (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates. (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-METTL3. (1:2000)
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METTL3 Mouse anti-Human Monoclonal (aa1-284) (Carrier-free) (OTI1B7) Antibody
Mouse, Rat, Human
WB
Unconjugated, Carrier-free
100 µg/$511
METTL3 Antibody - METTL3 antibody Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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METTL3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
METTL3 Antibody - METTL3 antibody Western blot of HepG2 Cell lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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METTL3 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Zebrafish, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Goat, Dog, Guinea pig, Bovine, Human, Monkey, Gibbon, Chimpanzee
WB
FITC Conjugated
100 µl/$469
METTL3 Antibody - Raji Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
METTL3 Rabbit anti-Human Polyclonal (aa206-255) Antibody
Human
WB
Unconjugated
100 µl/$397
METTL3 Antibody - Raji Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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METTL3 Rabbit anti-Human Polyclonal (aa206-255) (HRP) Antibody
Xenopus, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Rabbit, Mouse, Goat, Dog, Guinea pig, Bovine, Human, Monkey, Gibbon, Chimpanzee
WB
HRP Conjugated
100 µl/$442
METTL3 Antibody - Raji Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
METTL3 Rabbit anti-Human Polyclonal (aa206-255) (Biotin) Antibody
Xenopus, Zebrafish, Rat, Hamster, Bat, Pig, Horse, Rabbit, Mouse, Goat, Dog, Guinea pig, Bovine, Human, Monkey, Gibbon, Chimpanzee
WB
Biotin Conjugated
100 µl/$442
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).