METRNL

meteorin, glial cell differentiation regulator-like

Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures.

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Products

Antibodies (12)

ELISA Kits (11)

Proteins (6)

Type

Custom (1)

Primary (12)

Recombinant (6)

Sandwich (10)

Target

METRNL (29)

Reactivity

Human (11)

Mouse (9)

Rat (3)

Application

IHC (4)

IHC-P (4)

WB (9)

ELISA (8)

Host

rabbit (12)

Isotype

IgG (8)

Clonality

polyclonal pc (12)

Format

96-Well Strip Plate (11)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

Unconjugated (3)

Epitope

aa32-81 (4)

aa46-311 (4)

Publications

No (28)

Yes (1)

Sample Type

Bone Tissue Homogenates (1)

Cell Culture Supernatants (3)

Cell Lysates (4)

Plasma (10)

Serum (10)

Tissue Homogenates (6)

Urine (1)

Tag

6His, N-terminus (2)

6His-SUMO, N-terminus (1)

DDK (Flag) (1)

His (2)

Species

Human (4)

Mouse (2)

Source

E. coli (3)

HEK 293 Cells (1)

Mammalian Cells (1)

Yeast (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (2)

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Human METRNL (Sandwich ELISA) ELISA Kit - LS-F13315

(4.2) Rating

(3) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Bone Tissue Homogenates, Cell Culture Supernatants, Plasma, Serum, Urine

Price:

1 Plate/$783

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Rat METRNL (Sandwich ELISA) ELISA Kit - LS-F36056

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Mouse METRNL (Sandwich ELISA) ELISA Kit - LS-F39996

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum

Price:

1 Plate/$1,150

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METRNL Antibody LS-C681830

Antibody:

METRNL Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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METRNL Antibody (HRP) LS-C681832

Antibody:

METRNL Rabbit anti-Mouse Polyclonal (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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METRNL Antibody (Biotin) LS-C681831

Antibody:

METRNL Rabbit anti-Mouse Polyclonal (Biotin) Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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METRNL Antibody (FITC) LS-C681833

Antibody:

METRNL Rabbit anti-Mouse Polyclonal (FITC) Antibody

Reactivity:

Mouse

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

Mouse METRNL (Sandwich ELISA) ELISA Kit - LS-F12027

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Rat METRNL (Sandwich ELISA) ELISA Kit - LS-F25634

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.94 - 60 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$965

Select

METRNL Antibody (aa32-81) LS-C205541

Antibody:

METRNL Rabbit anti-Human Polyclonal (aa32-81) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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METRNL Antibody (aa32-81, HRP) LS-C476814

Antibody:

METRNL Rabbit anti-Human Polyclonal (aa32-81) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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METRNL Antibody (aa32-81, Biotin) LS-C476812

Antibody:

METRNL Rabbit anti-Human Polyclonal (aa32-81) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

METRNL Antibody (aa32-81, FITC) LS-C476813

Antibody:

METRNL Rabbit anti-Human Polyclonal (aa32-81) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

METRNL Antibody (aa46-311) LS-C371525

Antibody:

METRNL Rabbit anti-Human Polyclonal (aa46-311) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

METRNL Antibody (aa46-311, HRP) LS-C371526

Antibody:

METRNL Rabbit anti-Human Polyclonal (aa46-311) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

METRNL Antibody (aa46-311, Biotin) LS-C371528

Antibody:

METRNL Rabbit anti-Human Polyclonal (aa46-311) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

METRNL Antibody (aa46-311, FITC) LS-C371527

Antibody:

METRNL Rabbit anti-Human Polyclonal (aa46-311) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

Human METRNL Protein (Recombinant His) (aa46-311) - LS-G23413

Source:

Yeast

Tag:

His

Molecular Weight:

31.96 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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Mouse METRNL Protein (Recombinant 6His, N-terminus) (aa46-311) - LS-G64311

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human METRNL Protein (Recombinant 6His-SUMO, N-terminus) (aa46-311) - LS-G64255

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

Select

Human METRNL Protein (Recombinant 6His, N-terminus) (aa46-311) - LS-G64256

Source:

Mammalian Cells

Tag:

6His, N-terminus

Price:

100 µg/$1,009; 20 µg/$431; 1 mg/$3,451

Select

Mouse METRNL (Sandwich ELISA) ELISA Kit - LS-F53244

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

Select

Rat METRNL (Custom ELISA) ELISA Kit - LS-F20107

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Mouse METRNL (Sandwich ELISA) ELISA Kit - LS-F31738

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$717

Select

Human METRNL (Sandwich ELISA) ELISA Kit - LS-F25633

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$902

Viewing 1-25 of 29 product results

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