MER / MERTK

c-mer proto-oncogene tyrosine kinase

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands including LGALS3, TUB, TULP1 or GAS6. Regulates many physiological processes including cell survival, migration, differentiation, and phagocytosis of apoptotic cells (efferocytosis). Ligand binding at the cell surface induces autophosphorylation of MERTK on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with GRB2 or PLCG2 and induces phosphorylation of MAPK1, MAPK2, FAK/PTK2 or RAC1. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. Plays also an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 and SOCS3.

☰ Filters

Products

ELISA Kits (10)

Type

Custom (3)

Sandwich (7)

Target

MER / MERTK (10)

Reactivity

Human (6)

Mouse (3)

Rat (1)

Format

96-Well Microplate (3)

96-Well Strip Plate (7)

Publications

No (10)

Sample Type

Cell Culture Supernatants (5)

Cell Lysates (5)

Plasma (2)

Serum (5)

Tissue Homogenates (5)

Select

Human MER / MERTK (Sandwich ELISA) ELISA Kit - LS-F8050

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$834

Select

Human MER / MERTK (Sandwich ELISA) ELISA Kit - LS-F462

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.164 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$588

Select

Mouse MER / MERTK (Sandwich ELISA) ELISA Kit - LS-F24868

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Serum, Tissue Homogenates

Price:

1 Plate/$717

Select

Human MER / MERTK (Sandwich ELISA) ELISA Kit - LS-F24607

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

312 - 20000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Serum, Tissue Homogenates

Price:

1 Plate/$717

Select

Human MER / MERTK (Sandwich ELISA) ELISA Kit - LS-F37173

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human MER / MERTK (Sandwich ELISA) ELISA Kit - LS-F2690

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates

Price:

1 Plate/$795

Select

Mouse MER / MERTK (Custom ELISA) ELISA Kit - LS-F17192

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Human MER / MERTK (Custom ELISA) ELISA Kit - LS-F17193

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Rat MER / MERTK (Custom ELISA) ELISA Kit - LS-F17194

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$783

Select

Mouse MER / MERTK (Sandwich ELISA) ELISA Kit - LS-F2691

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Serum, Tissue Homogenates

Price:

1 Plate/$795

Viewing 1-10 of 10 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: ELISA Kits

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.