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MEP1B

meprin A, beta

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.

Gene Name: meprin A, beta
Family/Subfamily: Protease , Metallopeptidase M12A
Synonyms: MEP1B, Endopeptidase-2, Meprin A, beta, Meprin A subunit beta, Meprin beta, PABA peptide hydrolase, PPH beta, Meprin a beta, Meprin B
Target Sequences: NM_005925 NP_005916.2 Q16820

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Products
ELISA Kits (7)
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Sandwich (3)
MEP1B (7)
Human (4)
Mouse (2)
Rat (1)
96-Well Microplate (1)
96-Well Strip Plate (6)
No (7)
Cell Culture Supernatants (1)
Cell Lysates (2)
Plasma (2)
Serum (2)
Tissue Homogenates (3)
MEP1B ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
MEP1B ELISA Kit
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Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
MEP1B ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
MEP1B ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
MEP1B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$717
MEP1B ELISA Kit
Select
Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$700
MEP1B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$764
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).