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MEP1B

meprin A, beta

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.

Gene Name: meprin A, beta
Family/Subfamily: Protease , Metallopeptidase M12A
Synonyms: MEP1B, Endopeptidase-2, Meprin A, beta, Meprin A subunit beta, Meprin beta, PABA peptide hydrolase, PPH beta, Meprin a beta, Meprin B
Target Sequences: NM_005925 NP_005916.2 Q16820

☰ Filters
Products
Antibodies (16)
Primary (16)
MEP1B (16)
Human (7)
Mouse (3)
Rat (9)
IHC (1)
IHC-P (1)
WB (13)
ELISA (5)
rabbit (15)
mouse (1)
IgG (4)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (15)
09 (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Preservative Free (2)
Unconjugated (9)
No (16)
MEP1B Antibody - Immunohistochemistry of paraffin-embedded human small intestine at dilution 1:100
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MEP1B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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MEP1B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
Select
MEP1B Mouse anti-Human Monoclonal (Preservative Free) (09) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
Select
MEP1B Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
Select
MEP1B Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
MEP1B Antibody - Anti-MEP1B rabbit polyclonal antibody at 1:500 dilution. Lane A: A431 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 84 kDa. Observed band size: 105 kDa.
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MEP1B Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
WB
Unconjugated, Preservative Free
100 µl/$412
MEP1B Antibody - Western blot analysis of extracts of mouse kidney using MEP1B Polyclonal Antibody at dilution of 1:1000.
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MEP1B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
MEP1B Antibody - Western blot analysis of extracts of mouse kidney, using MEP1B antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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MEP1B Rabbit anti-Human Polyclonal Antibody
Mouse
WB
Unconjugated
20 µl/$275; 100 µl/$389
MEP1B Antibody - Western blot of recombinant MEP1B.
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MEP1B Rabbit anti-Rat Polyclonal Antibody
Rat
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
MEP1B Antibody - Western blot of recombinant MEP1B.
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MEP1B Rabbit anti-Rat Polyclonal (HRP) Antibody
Rat
WB
HRP Conjugated
100 µl/$335; 200 µl/$389; 500 µl/$566; 1 ml/$685; 2 ml/$922; 5 ml/$1,557
MEP1B Antibody - Western blot of recombinant MEP1B.
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MEP1B Rabbit anti-Rat Polyclonal (Biotin) Antibody
Rat
WB
Biotin Conjugated
100 µl/$316; 200 µl/$361; 500 µl/$511; 1 ml/$587; 2 ml/$809; 5 ml/$1,317
MEP1B Antibody - Western blot of recombinant MEP1B.
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MEP1B Rabbit anti-Rat Polyclonal (FITC) Antibody
Rat
WB
FITC Conjugated
100 µl/$345; 200 µl/$402; 500 µl/$594; 1 ml/$737; 2 ml/$976; 5 ml/$1,676
MEP1B Antibody - Western blot of recombinant MEP1B.
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MEP1B Rabbit anti-Rat Polyclonal (PE) Antibody
Rat
WB
PE Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
MEP1B Antibody - Western blot of recombinant MEP1B.
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MEP1B Rabbit anti-Rat Polyclonal (APC, Cy7) Antibody
Rat
WB
APC, Cy7 Conjugated
100 µl/$497; 200 µl/$632; 500 µl/$1,132; 1 ml/$1,369; 2 ml/$1,916; 5 ml/$3,592
MEP1B Antibody - Western blot of recombinant MEP1B.
Select
MEP1B Rabbit anti-Rat Polyclonal (APC) Antibody
Rat
WB
APC Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
MEP1B Antibody - Western blot of recombinant MEP1B.
Select
MEP1B Rabbit anti-Rat Polyclonal (Cy3) Antibody
Rat
WB
Cy3 Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
Viewing 1-16 of 16 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).