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MEMO1

mediator of cell motility 1

May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.

Gene Name: mediator of cell motility 1
Synonyms: MEMO1, C2orf4, Mediator of cell motility 1, MEMO, Protein MEMO1, NS5ATP7, C21orf19-like protein, CGI-27, Memo-1
Target Sequences: NM_015955 NP_057039.1 Q9Y316

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Products
Proteins (7)
Over-Expression Lysate (4)
Recombinant (3)
MEMO1 (7)
No (7)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (5)
Human (5)
293T Cells (2)
E. coli (2)
HEK 293 Cells (3)
Purified (1)
MEMO1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
MEMO1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
31.1 kDa
20 µg/$150
MEMO1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
33.6 kDa
20 µg/$150
MEMO1 Protein - Purified recombinant protein MEMO1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
33.6 kDa
20 µg/$1,107
MEMO1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
33.6 kDa
100 µg/$494
MEMO1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
31.1 kDa
100 µg/$494
MEMO1 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).