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MEF2D

myocyte enhancer factor 2D

Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis.

Gene Name: myocyte enhancer factor 2D
Synonyms: MEF2D, Myocyte enhancer factor 2D, MEF2D/DAZAP1 fusion
Target Sequences: NM_005920 NP_005911.1 Q14814

Publications (1)

1
FGF22 promotes generation of ribbon synapses through downregulating MEF2D. Shuna Li, Jingchun He, Yupeng Liu, Jun Yang. Aging. 2020 Apr;12:6456-6466. [Full Text Article] [PubMed:32271716] [PMC:PMC7185137]

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
MEF2D (5)
No (5)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
MEF2D Protein - Purified recombinant protein MEF2D was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
55.8 kDa
20 µg/$1,107
MEF2D Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MEF2D Protein - 12.5% SDS-PAGE of human MEF2D stained with Coomassie Blue
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Wheat Germ Extract
GST
82.28 kDa
10 µg/$479; 25 µg/$670
MEF2D Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
55.8 kDa
20 µg/$150
MEF2D Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
55.8 kDa
100 µg/$494
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).