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MEF2D

myocyte enhancer factor 2D

Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis.

Gene Name: myocyte enhancer factor 2D
Synonyms: MEF2D, Myocyte enhancer factor 2D, MEF2D/DAZAP1 fusion
Target Sequences: NM_005920 NP_005911.1 Q14814

Publications (1)

1
FGF22 promotes generation of ribbon synapses through downregulating MEF2D. Shuna Li, Jingchun He, Yupeng Liu, Jun Yang. Aging. 2020 Apr;12:6456-6466. [Full Text Article] [PubMed:32271716] [PMC:PMC7185137]

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MEF2D ELISA Kit
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).