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MED24 / TRAP100
mediator complex subunit 24
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
| Gene Name: | mediator complex subunit 24 |
| Synonyms: | MED24, ARC100, CRSP complex subunit 4, CRSP4, Mediator complex subunit 24, HTRAP100, KIAA0130, THRAP4, TRAP100, CRSP100, DRIP100 |
| Target Sequences: | NM_014815 NP_055630.2 O75448 |
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