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MED17 / TRAP80
mediator complex subunit 17
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
| Gene Name: | mediator complex subunit 17 |
| Synonyms: | MED17, CRSP77, CRSP complex subunit 6, CRSP6, DRIP77, Mediator complex subunit 17, TRAP80, ARC77, DRIP80 |
| Target Sequences: | NM_004268 NP_004259.3 Q9NVC6 |
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