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MED13L
mediator complex subunit 13-like
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.
| Gene Name: | mediator complex subunit 13-like |
| Synonyms: | MED13L, KIAA1025, PROSIT240, THRAP2, TRAP240L |
| Target Sequences: | AL133033 CAB61363.1 Q71F56 |
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