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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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ME2 / Malate Dehydrogenase 2

malic enzyme 2, NAD(+)-dependent, mitochondrial

ME2 / Malate Dehydrogenase 2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

Gene Name: malic enzyme 2, NAD(+)-dependent, mitochondrial
Synonyms: ME2, Malate dehydrogenase, Pyruvic-malic carboxylase, Malic enzyme 2, NAD-ME, ODS1
Target Sequences: NM_002396 NP_002387.1 P23368

Viewing 1-25 of 35 items
ME2 / Malate Dehydrogenase 2 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $425.00
ME2 / Malate Dehydrogenase 2 Antibody - Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using ME2 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200µl   $740.00
ME2 / Malate Dehydrogenase 2 Antibody - Staining RAW264.7 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IF, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
ME2 / Malate Dehydrogenase 2 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human placenta tissue using ME2 antibody.
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
Unconjugated
100µg   $305.00
ME2 / Malate Dehydrogenase 2 Antibody - Immunohistochemistry of paraffin-embedded human endometrial cancer at dilution of 1:100
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA, IHC, IHC-P
Unconjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA
HRP Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA
Biotin Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA
FITC Conjugated
50µg   $285.00; 100µg   $385.00
ME2 / Malate Dehydrogenase 2 Antibody - ME2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human rectum tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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Rabbit Polyclonal to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
ME2 / Malate Dehydrogenase 2 Antibody - ME2 Antibody (C-term) staining ME2 in human kidney tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.
Select
Mouse Monoclonal [clone 970CT2.1.1.2] (IgG1,k) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC-P, WB
Unconjugated
200µl   $325.00
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA, WB
Unconjugated
100µg   $375.00
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
ME2 / Malate Dehydrogenase 2 Antibody - Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $385.00
ME2 / Malate Dehydrogenase 2 Antibody
Select
Rabbit Polyclonal to Human ME2 / Malate Dehydrogenase 2
Human
WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $275.00
ME2 / Malate Dehydrogenase 2 Antibody - Western blot analysis of extract of various cells.
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
WB
Unconjugated
20µl   $215.00; 50µl   $235.00; 100µl   $295.00; 200µl   $385.00
ME2 / Malate Dehydrogenase 2 Antibody - Anti-ME2 rabbit polyclonal antibody at 1:500 dilution. Lane A: 293T Whole Cell Lysate. Lane B: Jurkat Whole Cell Lysate. Lane C: HeLa Whole Cell Lysate. Lane D: K562 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 65 kDa.
Select
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
WB
Unconjugated, Preservative Free
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
ME2 / Malate Dehydrogenase 2 Antibody - Western blot of ME2 / Malate Dehydrogenase 2 antibody.
Select
Rabbit Polyclonal to Human ME2 / Malate Dehydrogenase 2
Human
WB
Unconjugated
100µl   0.5mg/ml   $255.00; 200µl   0.5mg/ml   $305.00; 500µl   0.5mg/ml   $445.00; 1ml   0.5mg/ml   $530.00

Viewing 1-25 of 35 items


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).