MDK / Midkine

midkine (neurite growth-promoting factor 2)

Developmentally regulated, secreted growth factor homologous to pleiotrophin (PTN), which has heparin binding activity. Binds anaplastic lymphoma kinase (ALK) which induces ALK activation and subsequent phosphorylation of the insulin receptor substrate (IRS1), followed by the activation of mitogen-activated protein kinase (MAPK) and PI3-kinase, and the induction of cell proliferation. Involved in neointima formation after arterial injury, possibly by mediating leukocyte recruitment. Also involved in early fetal adrenal gland development.

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Products

Proteins (23)

Type

Over-Expression Lysate (8)

Recombinant (15)

Target

MDK / Midkine (23)

Publications

No (23)

Tag

6His, N-terminus (1)

GST (2)

His (1)

His, N-Terminal (1)

His-S (2)

His-T7 (1)

Myc-DDK (Flag) (11)

Species

Human (16)

Mouse (2)

Rat (1)

Source

293T Cells (4)

E. coli (11)

HEK 293 Cells (7)

Wheat Germ Extract (1)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (4)

Biologically Active

Biologically active (4)

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Human MDK / Midkine Protein (Recombinant) - LS-G131414

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

~14 kDa

Price:

20 µg/$301; 100 µg/$490; 1 mg/$1,891

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MDK / Midkine Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121834

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.4 kDa

Price:

100 µg/$494

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MDK / Midkine Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121833

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.4 kDa

Price:

100 µg/$494

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MDK / Midkine Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123604

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.4 kDa

Price:

100 µg/$494

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MDK / Midkine Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118013

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.4 kDa

Price:

100 µg/$494

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Human MDK / Midkine Protein (Recombinant GST) (Full Length) - LS-G29298

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

41.47 kDa

Price:

2 µg/$439

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Human MDK / Midkine Protein (Recombinant GST) (aa21-143) - LS-G22503

Source:

E. coli

Tag:

GST

Molecular Weight:

40.8 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human MDK / Midkine Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69753

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.4 kDa

Price:

20 µg/$1,107

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Human MDK / Midkine Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69754

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.4 kDa

Price:

20 µg/$1,107

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Human MDK / Midkine Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G69757

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.4 kDa

Price:

20 µg/$1,107

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Human MDK / Midkine Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85471

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.4 kDa

Price:

20 µg/$150

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Human MDK / Midkine Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85472

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.4 kDa

Price:

20 µg/$150

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Human MDK / Midkine Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85475

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.4 kDa

Price:

20 µg/$150

Select

Human MDK / Midkine Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85474

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.4 kDa

Price:

20 µg/$150

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Human MDK / Midkine Protein (Recombinant) (aa21-143) - LS-G5832

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

13.4 kDa

Price:

5 µg/$282; 100 µg/$957; 500 µg/$1,747

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Human MDK / Midkine Protein (Recombinant) - LS-G445

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

13.4 kDa

Price:

5 µg/$268; 20 µg/$349

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Human MDK / Midkine Protein (Recombinant His) - LS-G578

Source:

E. coli

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Mouse MDK / Midkine Protein (Recombinant) - LS-G376

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

13.3 kDa

Price:

5 µg/$268; 20 µg/$349

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Human MDK / Midkine Protein (Recombinant 6His, N-terminus) - LS-G26388

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

13 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Rat MDK / Midkine Protein (Recombinant His, N-Terminal) (Ala22-Asp140) - LS-G12514

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

18.8 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human MDK / Midkine Protein (Recombinant His-S) (aa22-143) - LS-G12526

Source:

E. coli

Tag:

His-S

Molecular Weight:

19.0 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Mouse MDK / Midkine Protein (Recombinant His-S) (aa22-140) - LS-G12531

Source:

E. coli

Tag:

His-S

Molecular Weight:

18.8 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human MDK / Midkine Protein (Recombinant His-T7) (aa22-143) - LS-G12532

Source:

E. coli

Tag:

His-T7

Molecular Weight:

17.1 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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