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MDFI / I-MF

myoD family inhibitor

Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways.

Gene Name: myoD family inhibitor
Synonyms: MDFI, I-MF, I-mfa, MyoD family inhibitor, Inhibitor of MyoD family a, Myogenic repressor I-mf
Target Sequences: NM_005586 NP_005577.1 Q99750

☰ Filters
Products
Antibodies (12)
Primary (12)
MDFI / I-MF (12)
Human (11)
Mouse (7)
Rat (4)
IHC (3)
IHC-P (1)
WB (9)
ELISA (5)
IF (2)
Peptide-ELISA (4)
rabbit (9)
mouse (1)
goat (2)
Product Group
IHCPlus (1)
IgG (8)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (11)
3B4 (1)
Unconjugated (12)
80-160 aa, Internal (1)
Pro134 (1)
aa103-152 (1)
aa148-162 (1)
aa2-13 (1)
No (12)
MDFI / I-MF Antibody - Western blot of MDFI antibody
Select
MDFI / I-MF Rabbit anti-Human Polyclonal (80-160 aa, Internal) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MDFI / I-MF Antibody - Anti-MDFI / I-MF antibody IHC staining of human bronchus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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MDFI / I-MF Goat anti-Human Polyclonal (aa148-162) Antibody
Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
MDFI / I-MF Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue  using MDFI Polyclonal Antibody at dilution of 1:55(×200)
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MDFI / I-MF Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MDFI / I-MF Antibody - Immunofluorescence of monoclonal antibody to MDFI on HeLa cell . [antibody concentration 10 ug/ml]
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MDFI / I-MF Mouse anti-Human Monoclonal (3B4) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
MDFI / I-MF Antibody - Staining HepG2 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
MDFI / I-MF Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MDFI / I-MF Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using MDFI Polyclonal Antibody at dilution of 1:50(×200)
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MDFI / I-MF Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MDFI / I-MF Antibody - Western blot analysis of extracts from Jurkat cells, using MDFI antibody.
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MDFI / I-MF Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
MDFI / I-MF Antibody - Western blot analysis of lysates from Jurkat cells, using MDFI Antibody. The lane on the right is blocked with the synthesized peptide.
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MDFI / I-MF Rabbit anti-Human Polyclonal (aa103-152) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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MDFI / I-MF Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
MDFI / I-MF Antibody - Western blot of MDFI (P134) pAb in extracts from Jurkat cells.
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MDFI / I-MF Rabbit anti-Human Polyclonal (Pro134) Antibody
Mouse, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
MDFI / I-MF Antibody - Western blot analysis of extracts of various cell lines, using MDFI antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 1s.
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MDFI / I-MF Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
Select
MDFI / I-MF Goat anti-Human Polyclonal (aa2-13) Antibody
Human
Peptide-ELISA
Unconjugated
100 µg/$401
Viewing 1-12 of 12 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).