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MCRS1 / MSP58
microspherule protein 1
Modulates the transcription repressor activity of DAXX by recruiting it to the nucleolus. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. May also be an inhibitor of TERT telomerase activity.
| Gene Name: | microspherule protein 1 |
| Synonyms: | MCRS1, 58 kDa microspherule protein, INO80 complex subunit Q, INO80 complex subunit J, INO80Q, MCRS2, Microspherule protein 1, MSP58, ICP22BP, p78 |
| Target Sequences: | NM_006337 NP_006328.2 Q96EZ8 |
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