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MCM8

minichromosome maintenance complex component 8

Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. May also play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G1 phase by recruiting CDC6 to the origin recognition complex (ORC). Binds chromatin throughout the cell cycle.

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Products

Antibodies (43)

Proteins (2)

Type

Primary (43)

Recombinant (2)

Target

MCM8 (45)

Reactivity

Human (43)

Mouse (14)

Rat (13)

Bat (9)

Bovine (11)

Chimpanzee (3)

Gibbon (12)

Guinea pig (6)

Hamster (9)

Horse (13)

Monkey (3)

Pig (13)

Rabbit (6)

Sheep (1)

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Application

IHC (5)

IHC-P (4)

WB (39)

ELISA (18)

IF (1)

Peptide-ELISA (1)

Host

rabbit (37)

mouse (6)

Isotype

IgG (27)

IgG1,k (6)

Clonality

monoclonal mc (6)

polyclonal pc (37)

Format

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (7)

FITC Conjugated (7)

HRP Conjugated (7)

PE Conjugated (2)

Unconjugated (18)

Epitope

aa144-193 (8)

aa322-350 (7)

aa71-120 (4)

aa717-766 (4)

C-Terminus (1)

aa646-735 (1)

aa809-840 (1)

Publications

No (45)

Tag

GST (1)

GST, N-terminus (1)

Species

Human (2)

Source

Wheat Germ Extract (2)

Purification

Purified (1)

Select

MCM8 Antibody LS-C802384

Antibody:

MCM8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

MCM8 Antibody (aa717-766) LS-C80163

Antibody:

MCM8 Rabbit anti-Human Polyclonal (aa717-766) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$424

Select

MCM8 Antibody (aa717-766, HRP) LS-C433978

Antibody:

MCM8 Rabbit anti-Human Polyclonal (aa717-766) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

MCM8 Antibody (aa717-766, Biotin) LS-C434588

Antibody:

MCM8 Rabbit anti-Human Polyclonal (aa717-766) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

MCM8 Antibody (aa717-766, FITC) LS-C434587

Antibody:

MCM8 Rabbit anti-Human Polyclonal (aa717-766) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

MCM8 Antibody (aa646-735) LS-C308923

Antibody:

MCM8 Mouse anti-Human Monoclonal (aa646-735) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

Select

MCM8 Antibody (HRP) LS-C543115

Antibody:

MCM8 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

Select

MCM8 Antibody (Biotin) LS-C522983

Antibody:

MCM8 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

Select

MCM8 Antibody (FITC) LS-C533027

Antibody:

MCM8 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

Select

MCM8 Antibody (PE) LS-C651227

Antibody:

MCM8 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

Select

MCM8 Antibody (APC) LS-C514768

Antibody:

MCM8 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

Select

MCM8 Antibody (C-Terminus) LS-C353858

Antibody:

MCM8 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Bovine, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

MCM8 Antibody LS-C502095

Antibody:

MCM8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

MCM8 Antibody LS-C753809

Antibody:

MCM8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

MCM8 Antibody (aa322-350) LS-C322917

Antibody:

MCM8 Rabbit anti-Human Polyclonal (aa322-350) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

MCM8 Antibody (aa322-350, Biotin) LS-C223254

Antibody:

MCM8 Rabbit anti-Human Polyclonal (aa322-350) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

MCM8 Antibody (aa322-350, FITC) LS-C223255

Antibody:

MCM8 Rabbit anti-Human Polyclonal (aa322-350) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

MCM8 Antibody (aa322-350, APC) LS-C223253

Antibody:

MCM8 Rabbit anti-Human Polyclonal (aa322-350) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MCM8 Antibody (aa322-350, PE) LS-C223257

Antibody:

MCM8 Rabbit anti-Human Polyclonal (aa322-350) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

MCM8 Antibody (aa322-350, Azide-free, HRP) LS-C223256

Antibody:

MCM8 Rabbit anti-Human Polyclonal (aa322-350) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

MCM8 Antibody LS-C781015

Antibody:

MCM8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

MCM8 Antibody LS-C341070

Antibody:

MCM8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

MCM8 Antibody LS-C488245

Antibody:

MCM8 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$412

Select

MCM8 Antibody (aa144-193) LS-C31741

Antibody:

MCM8 Rabbit anti-Human Polyclonal (aa144-193) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$397

Select

MCM8 Antibody (aa71-120) LS-C110194

Antibody:

MCM8 Rabbit anti-Human Polyclonal (aa71-120) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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