MCL1 / MCL 1

myeloid cell leukemia sequence 1 (BCL2-related)

Myeloid cell leukimia-1 (Mcl-1) is a member of the Bcl-2 family of proteins that can act to promote cell survival. While the mechanism by which Mcl-1 inhibits apoptosis is not known, it is thought that it may heterodimerize and neutralize pro-apoptotic members of the Bcl-2 family such as Bim or Bak. Mcl-1 was originally identified in differentiating myeloid cells, but has since been shown to be expressed in multiple cell types. Mcl-1 is essential for embryogenesis (5) and for the development and maintenance of B and T lymphocytes in animals. Mcl-1 exists as at least two distinct isoforms designated Mcl-1L and Mcl-1S. In marked contrast to the larger isoform of Mcl-1, overexpression of Mcl-1S promotes cell death.

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Products

Proteins (8)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (2)

Recombinant (5)

Target

MCL1 / MCL 1 (8)

Publications

No (8)

Tag

6His, N-terminus (1)

His (1)

His, N-Terminal (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Mouse (2)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (3)

Purification

Purified (1)

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Mouse MCL1 / MCL 1 Protein (Recombinant His, N-Terminal) (aa2-307) - LS-G15020

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

36.6 kDa

Price:

10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225

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Human MCL1 / MCL 1 Protein (Recombinant His) - LS-G1919

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human MCL1 / MCL 1 Protein (Recombinant His-T7) (aa6-328) - LS-G15019

Source:

E. coli

Tag:

His-T7

Molecular Weight:

38.4 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Mouse MCL1 / MCL 1 Protein (Recombinant His-SUMO) (Full Length) - LS-G20956

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

48.9 kD

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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MCL1 / MCL 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110542

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.2 kDa

Price:

100 µg/$494

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Human MCL1 / MCL 1 Protein (Over-Expression Cell Culture Supernatant 6His, N-terminus) (Phe2-Gly327) - LS-G26848

Source:

HEK 293 Cells

Tag:

6His, N-terminus

Molecular Weight:

36.4 kDa

Price:

200 µl/$283

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Human MCL1 / MCL 1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76756

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.2 kDa

Price:

20 µg/$150

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Human MCL1 / MCL 1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66016

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.2 kDa

Price:

20 µg/$1,107

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