MCFD2

multiple coagulation factor deficiency 2

MCFD2 is a soluble luminal protein with two calmodulin-like EF-hand motifs at its C-terminus. This protein forms a complex with LAMN1 (lectin mannose binding protein 1; also known as ERGIC-53) that facilitates the transport of coagulation factors V (FV) and VIII (FVIII) from the endoplasmic reticulum to the Golgi apparatus via an endoplasmic reticulum Golgi intermediate compartment (ERGIC). Mutations in this gene cause combined deficiency of FV and FVIII (F5F8D); a rare autosomal recessive bleeding disorder characterized by mild to moderate bleeding and coordinate reduction in plasma FV and FVIII levels. This protein has also been shown to maintain stem cell potential in adult central nervous system and is a marker for testicular germ cell tumors. The 3' UTR of this gene contains a transposon-like human repeat element named 'THE 1'. A processed RNA pseudogene of this gene is on chromosome 6p22.1. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Products

Antibodies (18)

Type

Primary (18)

Target

MCFD2 (18)

Reactivity

Human (18)

Rat (3)

Application

IHC (7)

IHC-P (2)

WB (11)

ELISA (13)

RNAi (1)

Host

rabbit (10)

mouse (8)

Isotype

IgG (8)

IgG1,k (7)

IgG2a,k (1)

Clonality

monoclonal mc (8)

polyclonal pc (10)

Clone

165CT13.1.6 (6)

3A5-G4 (1)

Format

APC Conjugated (2)

Azide-free (2)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Unconjugated (8)

Epitope

N-Terminus (7)

Publications

No (18)

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MCFD2 Antibody (N-Terminus) LS-C354416

Antibody:

MCFD2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

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MCFD2 Antibody (clone 3A5-G4) LS-C133826

Antibody:

MCFD2 Mouse anti-Human Monoclonal (3A5-G4) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, RNAi, WB

Format:

Unconjugated

Price:

100 µg/$423

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MCFD2 Antibody (N-Terminus) LS-C327907

Antibody:

MCFD2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

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MCFD2 Antibody (N-Terminus, Biotin) LS-C245038

Antibody:

MCFD2 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

200 µl/$952

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MCFD2 Antibody (N-Terminus, FITC) LS-C245037

Antibody:

MCFD2 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

200 µl/$952

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MCFD2 Antibody (N-Terminus, Azide-free, HRP) LS-C247702

Antibody:

MCFD2 Rabbit anti-Human Polyclonal (N-Terminus) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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MCFD2 Antibody (N-Terminus, APC) LS-C245036

Antibody:

MCFD2 Rabbit anti-Human Polyclonal (N-Terminus) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

APC Conjugated

Price:

200 µl/$952

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MCFD2 Antibody (N-Terminus, PE) LS-C245039

Antibody:

MCFD2 Rabbit anti-Human Polyclonal (N-Terminus) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

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MCFD2 Antibody (clone 165CT13.1.6) LS-C319176

Antibody:

MCFD2 Mouse anti-Human Monoclonal (165CT13.1.6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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MCFD2 Antibody (clone 165CT13.1.6, Biotin) LS-C232209

Antibody:

MCFD2 Mouse anti-Human Monoclonal (Biotin) (165CT13.1.6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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MCFD2 Antibody (clone 165CT13.1.6, FITC) LS-C232210

Antibody:

MCFD2 Mouse anti-Human Monoclonal (FITC) (165CT13.1.6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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MCFD2 Antibody (clone 165CT13.1.6, APC) LS-C232207

Antibody:

MCFD2 Mouse anti-Human Monoclonal (APC) (165CT13.1.6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

MCFD2 Antibody (clone 165CT13.1.6, PE) LS-C232212

Antibody:

MCFD2 Mouse anti-Human Monoclonal (PE) (165CT13.1.6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

MCFD2 Antibody (clone 165CT13.1.6, Azide-free, HRP) LS-C249333

Antibody:

MCFD2 Mouse anti-Human Monoclonal (Azide-free) (HRP) (165CT13.1.6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

MCFD2 Antibody LS-C164085

Antibody:

MCFD2 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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MCFD2 Antibody LS-C497084

Antibody:

MCFD2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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MCFD2 Antibody LS-C411697

Antibody:

MCFD2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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MCFD2 Antibody LS-C816671

Antibody:

MCFD2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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