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MC2R / ACTHR / ACTH Receptor

melanocortin 2 receptor (adrenocorticotropic hormone)

MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene.

Gene Name: melanocortin 2 receptor (adrenocorticotropic hormone)
Family/Subfamily: GPCR , Melanocortin
Synonyms: MC2R, ACTHR, ACTH receptor, ACTH-R, Adrenocorticotropic receptor, Adrenocorticotropin receptor, Melanocortin 2 receptor, Melanocortin receptor 2, MC2-R, MC2 receptor
Target Sequences: NM_000529 NP_000520.1 Q01718

Publications (2)

1
ACTH treatment promotes murine cardiac allograft acceptance. Jing Zhao , Liwei Jiang , Mayuko Uehara , Naima Banouni , Basmah S Al Dulaijan , Jamil Azzi , Takaharu Ichimura, Xiaofei Li , Petr Jarolim, Paolo Fiorina , Stefan G Tullius, Joren C Madsen , Vivek Kasinath , Reza Abdi. JCI insight. 2021 Jul;6:e143385. [Full Text Article] [PubMed:34236047] [PMC:PMC8410061] Related Antibodies: LS-C164069.
2
Morphologic and Molecular Characterization of Adrenals and Adrenal Rest Affected by Congenital Adrenal Hyperplasia. Vipula Kolli, Isabela Werneck da Cunha, SunA Kim, James R Iben, Ashwini Mallappa, Tianwei Li, Alison Gaynor, Steven L Coon, Martha M Quezado, Deborah P Merke. Frontiers in endocrinology. 2021 October;12:730947. [Full Text Article] [PubMed:34616364] [PMC:PMC8488225] Related Antibodies: LS-C164069.

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ELISA Kits (5)
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MC2R / ACTHR / ACTH Receptor (5)
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96-Well Strip Plate (5)
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Plasma (4)
Serum (4)
Tissue Homogenates (1)
MC2R / ACTHR / ACTH Receptor ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
MC2R / ACTHR / ACTH Receptor ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
MC2R / ACTHR / ACTH Receptor ELISA Kit
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Competitive EIA
96-Well Strip Plate
Monkey
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
MC2R / ACTHR / ACTH Receptor ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Chicken
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$627
MC2R / ACTHR / ACTH Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Tissue Homogenates
1 Plate/$893
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).