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Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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MBL2 / Mannose Binding Protein
mannose-binding lectin (protein C) 2, soluble
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. May bind DNA.
| Gene Name: | mannose-binding lectin (protein C) 2, soluble |
| Synonyms: | MBL2, Mannan-binding lectin, Mannan-binding protein, MBL2D, MBPD, MBL, Mannose-binding lectin, MBP-C, MBP1, COLEC1, Collectin-1, HSMBPC, Mannose-binding protein C |
| Target Sequences: | NM_000242 NP_000233.1 P11226 |
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