MBD5

methyl-CpG binding domain protein 5

MBD5 is a member of the methyl-CpG-binding domain (MBD) family. The MBD consists of about 70 residues and is the minimal region required for a methyl-CpG-binding protein binding specifically to methylated DNA. In addition to the MBD domain, this protein contains a PWWP domain (Pro-Trp-Trp-Pro motif), which consists of 100-150 amino acids and is found in numerous proteins that are involved in cell division, growth and differentiation. Mutations in this gene cause mental retardation autosomal dominant type 1. Haploinsufficiency of this gene is associated with a syndrome involving microcephaly, intellectual disabilities, severe speech impairment, and seizures. Alternatively spliced transcript variants have been found, but their full-length nature is not determined.

☰ Filters

Products

Proteins (1)

Type

Recombinant (1)

Target

MBD5 (1)

Publications

No (1)

Tag

GST (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

Purification

Purified (1)

Select

Human MBD5 Protein (Recombinant GST) (Full Length) - LS-G34430

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

50.93 kDa

Price:

10 µg/$479; 25 µg/$670

Viewing 1-1 of 1 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.