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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MATK

megakaryocyte-associated tyrosine kinase

MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.

Gene Name: megakaryocyte-associated tyrosine kinase
Family/Subfamily: Protein Kinase , Csk
Synonyms: MATK, Batk, CTK, Csk-homologous kinase, Hydroxyaryl-protein kinase, HYL, HYL tyrosine kinase, LSK, HHYLTK, Protein kinase HYL, Ntk, Tyrosine-protein kinase CTK, Tyrosylprotein kinase, Tyrosine kinase MATK, CHK, CSK homologous kinase, HYLTK
Target Sequences: NM_002378 NP_002369.2 P42679

Filtered by: None
Type
Over-Expression Lysate (6)
Recombinant (6)
Target
MATK (12)
Tag
GST,N-terminus (2)
His + T7 (1)
Myc + DDK (8)
Species
Human (8)
Rat (1)
Source
293T Cells (3)
E. coli (1)
HEK 293 Cells (5)
Insect Cells (1)
Wheat Germ Extract (2)
Biologically Active
Biologically active (1)
Showing 1-12 of 12 results

Human MATK Protein (Recombinant GST,N-terminus) (aa422-507) - LS-G59187
Wheat Germ Extract
GST,N-terminus
10µg  $425.00; 25µg  $590.00
12.5% SDS-PAGE Stained with Coomassie Blue.

Human MATK Protein (Recombinant GST,N-terminus) (aa1-100) - LS-G59188
Wheat Germ Extract
GST,N-terminus
10µg  $425.00; 25µg  $590.00
12.5% SDS-PAGE Stained with Coomassie Blue.

MATK Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G118018
HEK 293 Cells
Myc + DDK
56.6 kDa
100µg  $475.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Rat MATK Protein (Recombinant His + T7) (aa1-173) - LS-G25022
E. coli
His + T7
23.3 kDa
10µg  $255.00; 50µg  $405.00; 100µg  $495.00; 200µg  $740.00; 1mg  $1,890.00
Recombinant Megakaryocyte Associated Tyrosine Kinase By SDS-PAGE

Human MATK Protein (Recombinant Myc + DDK) (Full Length) - LS-G66188
HEK 293 Cells
Myc + DDK
51.7 kDa
20µg  $815.00
Purified recombinant protein MATK was analyzed by SDS-PAGE gel and Coomassie Blue Staining

Human MATK Protein (Recombinant Myc + DDK) (Full Length) - LS-G66187
HEK 293 Cells
Myc + DDK
56.3 kDa
20µg  $815.00
Purified recombinant protein MATK was analyzed by SDS-PAGE gel and Coomassie Blue Staining

Human MATK Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G77132
293T Cells
Myc + DDK
56.6 kDa
20µg  $195.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human MATK Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G77133
293T Cells
Myc + DDK
51.7 kDa
20µg  $195.00

Human MATK Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G77134
293T Cells
Myc + DDK
56.3 kDa
20µg  $195.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

MATK Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G107009
HEK 293 Cells
Myc + DDK
56.3 kDa
100µg  $475.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

MATK Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G107013
HEK 293 Cells
Myc + DDK
51.7 kDa
100µg  $345.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human MATK Protein (Recombinant) - LS-G131796
Insect Cells
None
Biologically active
~83 kDa
10µg  $365.00
Showing 1-12 of 12 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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