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MAST205 / MAST2

microtubule associated serine/threonine kinase 2

Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation.

Gene Name: microtubule associated serine/threonine kinase 2
Family/Subfamily: Protein Kinase , MAST
Synonyms: MAST2, KIAA0807, MTSSK, RP4-533D7.1, MAST205
Target Sequences: NM_015112 NP_055927.2 Q6P0Q8

Publications (1)

1
Molecular Profiling of Vascular Remodeling in Chronic Pulmonary Disease. Lavinia Neubert, Paul Borchert, Helge Stark, Anne Hoefer, Jens Vogel-Claussen, Gregor Warnecke, Holger Eubel, Patrick Kuenzler, Hans-Heinrich Kreipe, Marius M Hoeper, Mark Kuehnel, Danny Jonigk. The American journal of pathology. 2020 July;190:1382-1396. [Full Text Article] [PubMed:32275906] Related Antibodies: LS-C808430.

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MAST205 / MAST2 ELISA Kit
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0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).