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MARK1 / MARK

MAP/microtubule affinity-regulating kinase 1

Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).

Gene Name: MAP/microtubule affinity-regulating kinase 1
Family/Subfamily: Protein Kinase , MARK
Synonyms: MARK1, KIAA1477, Par1c, PAR1 homolog c, MARK, Par-1c
Target Sequences: NM_018650 NP_061120.3 Q9P0L2

Publications (1)

1
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA. Molecular and cellular biology. 2008 28:2414-25. [PubMed:18227155] [PMC:PMC2268441] Related Antibodies: LS-C98353.

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Products
Antibodies (42)
Primary (42)
MARK1 / MARK (42)
Human (41)
Mouse (28)
Rat (4)
Bat (2)
Bovine (1)
Dog (1)
Hamster (1)
Horse (1)
Monkey (3)
Rabbit (3)
IHC (23)
IHC-P (7)
WB (37)
Flo (6)
ELISA (29)
Peptide-ELISA (3)
rabbit (41)
goat (1)
Product Group
IHCPlus (3)
IgG (33)
polyclonal pc (42)
APC Conjugated (4)
Azide-free (4)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (4)
Unconjugated (22)
aa6-40 (7)
aa600-627 (7)
aa643-674 (7)
aa671-700 (7)
N-Terminus (2)
Internal (1)
aa448-460 (1)
No (41)
Yes (1)
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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MARK1 / MARK Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
MARK1 / MARK Antibody - The anti-MARK1 C-term antibody is used in Western blot to detect MARK1 in, from left to right, HeLa, T47D, and mouse brain cell line/ tissue lysate.
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MARK1 / MARK Rabbit anti-Human Polyclonal (aa671-700) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
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MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
MARK1 / MARK Antibody - Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100
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MARK1 / MARK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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MARK1 / MARK Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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MARK1 / MARK Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
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MARK1 / MARK Rabbit anti-Human Polyclonal (aa6-40) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
MARK1 / MARK Rabbit anti-Human Polyclonal (aa6-40) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
MARK1 / MARK Rabbit anti-Human Polyclonal (aa6-40) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
MARK1 / MARK Rabbit anti-Human Polyclonal (aa6-40) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
MARK1 / MARK Rabbit anti-Human Polyclonal (aa6-40) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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MARK1 / MARK Rabbit anti-Human Polyclonal (aa6-40) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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MARK1 / MARK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
MARK1 / MARK Antibody - MARK Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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MARK1 / MARK Rabbit anti-Human Polyclonal (aa643-674) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
MARK1 / MARK Antibody
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MARK1 / MARK Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
Select
MARK1 / MARK Rabbit anti-Mouse Polyclonal (aa600-627) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Select
MARK1 / MARK Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
MARK1 / MARK Antibody - Immunohistochemistry of paraffin-embedded Human thyroid cancer using MARK1 Polyclonal Antibody at dilution of 1:30.
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MARK1 / MARK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MARK1 / MARK Antibody - Immunohistochemistry of paraffin-embedded mouse lung tissue.
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MARK1 / MARK Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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MARK1 / MARK Rabbit anti-Human Polyclonal (aa671-700) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
Viewing 26-42 of 42 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).