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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
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MARK1 / MARK

MAP/microtubule affinity-regulating kinase 1

Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).

Gene Name: MAP/microtubule affinity-regulating kinase 1
Family/Subfamily: Protein Kinase , MARK
Synonyms: MARK1, KIAA1477, Par1c, PAR1 homolog c, MARK, Par-1c
Target Sequences: NM_018650 NP_061120.3 Q9P0L2

Publications (1)

1
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA. Molecular and cellular biology. 2008 28:2414-25. [PubMed:18227155] [PMC:PMC2268441] Related Antibodies: LS-C98353.


MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Horse, Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Horse, Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Horse, Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Horse, Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Horse, Human, Monkey
IHC, IHC-P
PE Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Horse, Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg   0.75mg/ml   $425.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
PE Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg   50µl   1mg/ml   $425.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Bat, Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Bat, Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Bat, Human, Monkey
IHC, IHC-P
APC Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Bat, Human, Monkey
IHC, IHC-P
AP Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Bat, Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl   $650.00
MARK1 / MARK Antibody - Anti-MARK1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Bat, Human, Monkey
IHC, IHC-P
PE Conjugated
100µl   $650.00
MARK1 / MARK Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with MARK1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Rabbit Polyclonal to Human MARK1 / MARK
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
MARK1 / MARK Antibody - The anti-MARK1 C-term antibody is used in Western blot to detect MARK1 in, from left to right, HeLa, T47D, and mouse brain cell line/ tissue lysate.
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Rabbit Polyclonal to Human MARK1 / MARK
Mouse, Human
WB
Unconjugated
400µl   $325.00
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Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Human
ELISA, Flo, IHC, WB
Unconjugated
200µl   $590.00
MARK1 / MARK Antibody - Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100
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Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl   $235.00; 100µl   $285.00
Viewing 1-25 of 64 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).