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Unfortunately, the antibody (ID:36801) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



MAPK9 / JNK2

mitogen-activated protein kinase 9

Serine/threonine-protein kinase involved in various processes such as cell proliferation, differentiation, migration, transformation and programmed cell death. Extracellular stimuli such as proinflammatory cytokines or physical stress stimulate the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. In this cascade, two dual specificity kinases MAP2K4/MKK4 and MAP2K7/MKK7 phosphorylate and activate MAPK9/JNK2. In turn, MAPK9/JNK2 phosphorylates a number of transcription factors, primarily components of AP-1 such as JUN and ATF2 and thus regulates AP-1 transcriptional activity. In response to oxidative or ribotoxic stresses, inhibits rRNA synthesis by phosphorylating and inactivating the RNA polymerase 1-specific transcription initiation factor RRN3. Promotes stressed cell apoptosis by phosphorylating key regulatory factors including TP53 and YAP1. In T-cells, MAPK8 and MAPK9 are required for polarized differentiation of T-helper cells into Th1 cells. Upon T-cell receptor (TCR) stimulation, is activated by CARMA1, BCL10, MAP2K7 and MAP3K7/TAK1 to regulate JUN protein levels. Plays an important role in the osmotic stress-induced epithelial tight-junctions disruption. When activated, promotes beta-catenin/CTNNB1 degradation and inhibits the canonical Wnt signaling pathway. Participates also in neurite growth in spiral ganglion neurons.MAPK9 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to JUN, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.

Gene Name: mitogen-activated protein kinase 9
Family/Subfamily: Protein Kinase , MAPK
Synonyms: MAPK9, C-Jun kinase 2, C-Jun N-terminal kinase 2, JNK2B, JNK2, JNK2ALPHA, MAP kinase 9, p54a, JNK2BETA, PRKM9, SAPK, MAPK 9, p54aSAPK, SAPK1a, JNK-55, JNK2A, Jun kinase
Target Sequences: NM_002752 NP_002743.3 P45984

Publications (1)

1
Cerebral ischemia provokes a profound exchange of activated JNK isoforms in brain mitochondria. Zhao Y, Herdegen T. Molecular and cellular neurosciences. 2009 41:186-95. (WB, IP) [PubMed:19289169]

Filtered By: None
Target
mapk9-jnk2 (63)
Reactivity
Human (61)
Mouse (34)
Rat (24)
Bat (7)
Bovine (5)
Chicken (5)
Chimpanzee (3)
Dog (10)
Gibbon (3)
Goat (4)
Guinea pig (6)
Hamster (2)
Horse (5)
Monkey (9)
Pig (7)
Rabbit (8)
Sheep (1)
Xenopus (4)
Zebrafish (4)
Application
IHC (35)
IHC-P (15)
WB (58)
Flo (1)
ELISA (24)
ICC (5)
IF (9)
IP (8)
Peptide-ELISA (3)
Host
rabbit (51)
mouse (8)
goat (2)
chicken (1)
sheep (1)
Isotype
IgG (33)
IgG1 (5)
IgG1,k (1)
Clonality
monoclonal mc (8)
polyclonal pc (55)
Clone
1A1 (1)
1C1-3A8 (1)
2D11 (1)
2G3 (1)
2H3 (1)
4D1 (1)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (42)
Epitope
aa130-387 (10)
aa206-233 (8)
aa1-424 (4)
aa40-89 (4)
aa217-230 (2)
C-Terminus (1)
Internal (1)
N-Terminus (1)
Phe280 (1)
Thr183/ (1)
aa1-16 (1)
aa181-185 (1)
aa220-300 (1)
aa246-295 (1)
aa257-288 (1)
aa373-389 (1)
pThr183 (1)
pThr183/Tyr185 (1)
Publications
No (63)
Showing 1-25 out of 63 results
Anti-MAPK9 / JNK2 Antibody (clone 1C1-3A8) IHC-plus™ LS-B6137
Anti-MAPK9 / JNK2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6137 concentration 5 ug/ml.
Western blot of MAPK9 expression in transfected 293T cell line by MAPK9 monoclonal antibody LS-B6137

Mouse Monoclonal [clone 1C1-3A8] (IgG1,k) to Human MAPK9 / JNK2
Human
ELISA IHC IHC-P WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody (aa373-389) IHC-plus™ LS-B2052
Anti-MAPK9 / JNK2 antibody IHC of human brain-cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2052 concentration 10 ug/ml.
Western blot analysis for JNK2 using antibody at 2 ug/ml on 20 ugs of A431 whole cell lysate.

Rabbit Polyclonal (IgG) to Human MAPK9 / JNK2
Rabbit, Bovine, Pig, Bat, Human
IHC IHC-P WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody (N-Terminus) IHC-plus™ LS-B1829
Anti-MAPK9 / JNK2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1829 concentration 20 ug/ml.

Rabbit Polyclonal to Human MAPK9 / JNK2
Human
ELISA IHC IHC-P WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody (aa217-230) IHC-plus™ LS-B11182
Anti-MAPK9 / JNK2 / SAPK antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B11182 concentration 5 ug/ml.
MAPK9 antibody (0.5 ug/ml) staining of Human Cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Goat Polyclonal to Human MAPK9 / JNK2
Rabbit, Mouse, Rat, Bat, Human, Monkey
IHC IHC-P Peptide-ELISA WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody (phospho-Thr183) LS-C34197
Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using SAPK/JNK(Phospho-Thr183) antibody (left) or the same antibody preincubated with blocking peptide (right).
Western blot of extracts from 293 cells using SAPK/JNK(Phospho-Thr183) antibody(Lane 2) and the same antibody preincubated with blocking peptide(Lane1).

Rabbit Polyclonal (IgG) to Human MAPK9 / JNK2
Mouse, Rat, Human
IHC IHC-P WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody (clone 2G3) LS-C174574
IHC of paraffin-embedded Human pancreas tissue using anti-MAPK9 mouse monoclonal antibody.
IHC of paraffin-embedded Human tonsil using anti-MAPK9 mouse monoclonal antibody.

Mouse Monoclonal [clone 2G3] (IgG1) to Human MAPK9 / JNK2
Mouse, Dog, Rat, Human, Monkey
IF IHC IHC-P WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody (clone 4D1) LS-C174575
IHC of paraffin-embedded Human pancreas tissue using anti-MAPK9 mouse monoclonal antibody.
IHC of paraffin-embedded Human tonsil using anti-MAPK9 mouse monoclonal antibody.

Mouse Monoclonal [clone 4D1] (IgG1) to Human MAPK9 / JNK2
Mouse, Dog, Human
IF IHC IHC-P WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody (clone 1A1) LS-C174576
IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-MAPK9 mouse monoclonal antibody.
IHC of paraffin-embedded Human pancreas tissue using anti-MAPK9 mouse monoclonal antibody.

Mouse Monoclonal [clone 1A1] (IgG1) to Human MAPK9 / JNK2
Mouse, Dog, Rat, Human, Monkey
IF IHC IHC-P WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody LS-C335141
Immunohistochemistry of paraffin-embedded human breast cancer tissue.
Immunohistochemistry of paraffin-embedded mouse brain tissue.

Rabbit Polyclonal (IgG) to Human MAPK9 / JNK2
Mouse, Rat, Human
ICC IF IHC IP WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody LS-C487867

Rabbit Polyclonal to Human MAPK9 / JNK2
Human
ELISA ICC IF IHC IHC-P IP WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody (C-Terminus) IHC-plus™ LS-B1828
Anti-MAPK9 / JNK2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1828 concentration 20 ug/ml.

Rabbit Polyclonal to Human MAPK9 / JNK2
Human
ELISA IHC IHC-P WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody LS-C487863

Rabbit Polyclonal to Human MAPK9 / JNK2
Human
ELISA ICC IF IP WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody (Thr183/) LS-C190216

Rabbit Polyclonal (IgG) to Human MAPK9 / JNK2
Mouse, Rat, Human
ICC IHC IP WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody LS-C487864

Mouse Monoclonal to Human MAPK9 / JNK2
Human
Flo ICC IF
Unconjugated
Anti-MAPK9 / JNK2 Antibody (clone 2H3) LS-C174557
IHC of paraffin-embedded Human breast tissue using anti-MAPK9 mouse monoclonal antibody.
IHC of paraffin-embedded Human pancreas tissue using anti-MAPK9 mouse monoclonal antibody.

Mouse Monoclonal [clone 2H3] (IgG1) to Human MAPK9 / JNK2
Human
IHC IHC-P WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody (clone 2D11) LS-C174560
IHC of paraffin-embedded Human pancreas tissue using anti-MAPK9 mouse monoclonal antibody.
IHC of paraffin-embedded Human tonsil using anti-MAPK9 mouse monoclonal antibody.

Mouse Monoclonal [clone 2D11] (IgG1) to Human MAPK9 / JNK2
Mouse, Dog, Rat, Human, Monkey
IHC IHC-P WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody (aa206-233) LS-C329815

Rabbit Polyclonal (IgG) to Mouse MAPK9 / JNK2
Mouse, Human
ELISA IHC WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody (aa206-233, Biotin) LS-C215734

Rabbit Polyclonal (IgG) to Mouse MAPK9 / JNK2
Mouse, Human
ELISA IHC WB
Biotin Conjugated
Anti-MAPK9 / JNK2 Antibody (aa206-233, FITC) LS-C215735

Rabbit Polyclonal (IgG) to Mouse MAPK9 / JNK2
Mouse, Human
ELISA IHC WB
FITC Conjugated
Anti-MAPK9 / JNK2 Antibody (aa206-233, Azide-free, HRP) LS-C215737

Rabbit Polyclonal (IgG) to Mouse MAPK9 / JNK2
Mouse, Human
ELISA IHC WB
HRP Conjugated, Azide-free
Anti-MAPK9 / JNK2 Antibody (aa206-233, APC) LS-C215733

Rabbit Polyclonal (IgG) to Mouse MAPK9 / JNK2
Mouse, Human
ELISA IHC WB
APC Conjugated
Anti-MAPK9 / JNK2 Antibody (aa206-233, AP) LS-C215732

Rabbit Polyclonal (IgG) to Mouse MAPK9 / JNK2
Mouse, Human
ELISA IHC WB
AP Conjugated
Anti-MAPK9 / JNK2 Antibody (aa206-233, PE) LS-C215736

Rabbit Polyclonal (IgG) to Mouse MAPK9 / JNK2
Mouse, Human
ELISA IHC WB
PE Conjugated
Anti-MAPK9 / JNK2 Antibody LS-C666538

Rabbit Polyclonal (IgG) to Human MAPK9 / JNK2
Human
ELISA IF WB
Unconjugated
Anti-MAPK9 / JNK2 Antibody (aa220-300) LS-C384238
Western blot of JNK2 antibody

Rabbit Polyclonal (IgG) to Human MAPK9 / JNK2
Mouse, Rat, Human
ELISA IHC WB
Unconjugated

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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