MAPK6 / ERK3

mitogen-activated protein kinase 6

ERK3, a MAPK type protein kinase, has been associated with the ERK MAPKs based on similarity of the catalytic domain. Compared to ERK1/2, ERK 3 lacks the activating tyrosine phosphorylation site and contains only a serine which is phosphorylated by MEK. ERK3 is primarily localized to the nucleus where it is believed to phosphorylate substrates in response to cell stress and damage. Specific ERK3 substrates are uncertain; however, studies have shown that ERK3 does not phosphorylate ERK1/2 substrates. The ERK3 gene maps to chromosome 15q21, a region associated with chromosomal abnormalities in acute nonlymphoblastic leukemias. Additionally, ERK3 kinase activity has been reported to be increased in colorectal cancers.

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ELISA Kits (4)

Type

Cell-Based (1)

Cell-Based Phosphorylation (1)

Sandwich (2)

Target

MAPK6 / ERK3 (4)

Reactivity

Human (3)

Mouse (2)

Rat (2)

Monkey (1)

Format

96-Well Microplate (2)

96-Well Strip Plate (2)

Publications

No (4)

Sample Type

Adherent Cell Cultures (2)

Plasma (1)

Serum (1)

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Monkey MAPK6 / ERK3 (Sandwich ELISA) ELISA Kit - LS-F43700

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$728

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Human MAPK6 / ERK3 (Sandwich ELISA) ELISA Kit - LS-F38028

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse/Human/Rat Phospho-MAPK6 / ERK3 (Ser189) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1357

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse/Human/Rat MAPK6 / ERK3 (Cell-Based ELISA) ELISA Kit - LS-F1974

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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