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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MAPK4 / ERK4

mitogen-activated protein kinase 4

Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. May promote entry in the cell cycle.

Gene Name: mitogen-activated protein kinase 4
Family/Subfamily: Protein Kinase , MAPK
Synonyms: MAPK4, ERK-4, Erk3-related, Erk4, MAP kinase isoform p63, PRKM4, RMNK2, MAP kinase 4, ERK3, MAPK 4, p63-MAPK, p63MAPK
Target Sequences: NM_002747 NP_002738.2 P31152

Filtered by: None
Target
MAPK4 / ERK4 (41)
Reactivity
Human (40)
Mouse (23)
Rat (4)
Bat (4)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (4)
Horse (4)
Pig (4)
Zebrafish (4)
Application
IHC (30)
IHC-P (7)
WB (39)
ELISA (20)
ICC (1)
IF (5)
IP (7)
Host
rabbit (28)
mouse (5)
sheep (8)
Isotype
IgG (26)
IgG1 (2)
IgG2a,k (1)
IgG2b (2)
Clonality
monoclonal mc (5)
polyclonal pc (36)
Clone
2B10 (1)
OTI2D7 (2)
OTI2F4 (2)
Format
AP Conjugated (3)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (4)
Carrier-free (2)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (20)
Epitope
aa527-557 (8)
aa67-94 (8)
aa287-336 (4)
C-Terminus (1)
aa1-326 (1)
aa348-587 (1)
aa537-566 (1)
aa72-101 (1)
Publications
No (41)
Showing 1-25 of 41 results

IHC-plus™ MAPK4 / ERK4 Antibody (aa1-326) LS-B10768
Rabbit Polyclonal (IgG) to Human MAPK4 / ERK4
Human
ICC, IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Anti-MAPK4 / ERK4 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 7.5 ug/ml.
Immunofluorescence of paraformaldehyde-fixed HeLa using MAPK4 antibody at 1:200 dilution.

MAPK4 / ERK4 Antibody (aa67-94) LS-C164470
Rabbit Polyclonal to Mouse MAPK4 / ERK4
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Mouse Mapk4 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded mouse heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Mouse Mapk4 Antibody western blot of mouse brain tissue lysates (35 ug/lane). The Mapk4 antibody detected the Mapk4 protein (arrow).

MAPK4 / ERK4 Antibody (aa527-557) LS-C99954
Rabbit Polyclonal to Human MAPK4 / ERK4
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ERK4 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of anti-ERK4 antibody in mouse brain tissue lysate. ERK4 (arrow) was detected using purified antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

MAPK4 / ERK4 Antibody (clone OTI2D7) LS-C174528
Mouse Monoclonal [clone OTI2D7] (IgG2b) to Human MAPK4 / ERK4
Human
IF, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Human Kidney tissue using anti-MAPK4 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-MAPK4 mouse monoclonal antibody.

MAPK4 / ERK4 Antibody (clone OTI2D7, Carrier-free) LS-C797660
Mouse Monoclonal [clone OTI2D7] (IgG2b) to Human MAPK4 / ERK4
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
IHC of paraffin-embedded Human Kidney tissue using anti-MAPK4 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human kidney tissue using anti-MAPK4 mouse monoclonal antibody.

MAPK4 / ERK4 Antibody (clone OTI2F4) LS-C337997
Mouse Monoclonal [clone OTI2F4] (IgG1) to Human MAPK4 / ERK4
Human
IF, IHC, IHC-P, WB
Unconjugated
100µl 1mg/ml  $345.00
IHC of paraffin-embedded Human pancreas tissue using anti-MAPK4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Anti-MAPK4 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPK4.

MAPK4 / ERK4 Antibody (clone OTI2F4, Carrier-free) LS-C787904
Mouse Monoclonal [clone OTI2F4] (IgG1) to Human MAPK4 / ERK4
Human
IF, IHC, WB
Unconjugated, Carrier-free
100µg  $395.00
IHC of paraffin-embedded Human pancreas tissue using anti-MAPK4 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
Anti-MAPK4 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY MAPK4.

MAPK4 / ERK4 Antibody (aa348-587) LS-C376077
Rabbit Polyclonal (IgG) to Human MAPK4 / ERK4
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.

MAPK4 / ERK4 Antibody (aa67-94) LS-C322842
Rabbit Polyclonal (IgG) to Mouse MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

MAPK4 / ERK4 Antibody (aa67-94, Biotin) LS-C215727
Rabbit Polyclonal (IgG) to Mouse MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200µl  $740.00

MAPK4 / ERK4 Antibody (aa67-94, FITC) LS-C215728
Rabbit Polyclonal (IgG) to Mouse MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200µl  $740.00

MAPK4 / ERK4 Antibody (aa67-94, AP) LS-C215725
Rabbit Polyclonal (IgG) to Mouse MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
AP Conjugated
200µl  $740.00

MAPK4 / ERK4 Antibody (aa67-94, APC) LS-C215726
Rabbit Polyclonal (IgG) to Mouse MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200µl  $740.00

MAPK4 / ERK4 Antibody (aa67-94, Azide-free, HRP) LS-C215729
Rabbit Polyclonal (IgG) to Mouse MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

MAPK4 / ERK4 Antibody (aa67-94, PE) LS-C215730
Rabbit Polyclonal (IgG) to Mouse MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200µl  $740.00

MAPK4 / ERK4 Antibody (aa527-557) LS-C319092
Rabbit Polyclonal (IgG) to Human MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

MAPK4 / ERK4 Antibody (aa527-557, Biotin) LS-C219989
Rabbit Polyclonal (IgG) to Human MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200µl  $740.00

MAPK4 / ERK4 Antibody (aa527-557, FITC) LS-C219990
Rabbit Polyclonal (IgG) to Human MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200µl  $740.00

MAPK4 / ERK4 Antibody (aa527-557, APC) LS-C219986
Rabbit Polyclonal (IgG) to Human MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200µl  $740.00

MAPK4 / ERK4 Antibody (aa527-557, AP) LS-C219987
Rabbit Polyclonal (IgG) to Human MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
AP Conjugated
200µl  $740.00

MAPK4 / ERK4 Antibody (aa527-557, Azide-free, HRP) LS-C219991
Rabbit Polyclonal (IgG) to Human MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

MAPK4 / ERK4 Antibody (aa527-557, PE) LS-C219992
Rabbit Polyclonal (IgG) to Human MAPK4 / ERK4
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200µl  $740.00

MAPK4 / ERK4 Antibody (clone 2B10) LS-C197994
Mouse Monoclonal [clone 2B10] (IgG2a,k) to Human MAPK4 / ERK4
Human
ELISA, IF
Unconjugated
100µg  $365.00
Immunofluorescence of monoclonal antibody to MAPK4 on HeLa cell . [antibody concentration 10 ug/ml]

MAPK4 / ERK4 Antibody (aa72-101) LS-C100884
Rabbit Polyclonal to Human MAPK4 / ERK4
Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with MAPK4 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of MAPK4 Antibody in 293 cell line lysates (35 ug/lane). MAPK4 (arrow) was detected using the purified antibody.

MAPK4 / ERK4 Antibody (C-Terminus) LS-C37298
Sheep Polyclonal (IgG) to Human MAPK4 / ERK4
Human
IHC, IP, WB
Unconjugated
250µg  $590.00
Showing 1-25 of 41 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).