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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
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MAPK14 / p38

mitogen-activated protein kinase 14

MAP kinase p38 alpha, a MAPK type protein kinase, is an environmental stress- and inflammatory cytokine-induced kinase that is associated with the regulation of gene expression, cell proliferation and cell death. p38alpha is phosphorylated by MEK3/MAP2K3 or MKK6/MAP2K6. Activated p38alpha either remains in the cytosol, where it phosphorylates cytosolic proteins including MNK1/2, PLA2 and PRAK, or translocates to the nucleus, where it phosphorylates several substrates, including ATF2, CHOP/GADD153, MAPKAPK-2 and -3, MEF2-A and -C, MSK, Myc binding partner Max and Sap-1a. At least four protein isoforms, resulting from alternatively spliced transcript variants of this gene, have been identified - 297, 307 and two isoforms of 360 amino acids with differing internal segments.

Gene Name: mitogen-activated protein kinase 14
Family/Subfamily: Protein Kinase , MAPK
Synonyms: MAPK14, CSAID-binding protein, CSBP2, CSPB1, CSBP1, Csaids binding protein, CSBP, EXIP, MAP kinase 14, MAP kinase p38 alpha, MAX-interacting protein 2, MAPK 14, p38 alpha, PRKM15, PRKM14, RK, SAPK2A, MAP kinase MXI2, Mxi2, p38ALPHA, p38, p38 MAP kinase, p38alpha Exip
Target Sequences: NM_001315 NP_001306.1 Q16539

Publications (3)

1
Preconditioning by inhaled nitric oxide prevents hyperoxic and ischemia/reperfusion injury in rat lungs. Waldow T, Witt W, Ulmer A, Janke A, Alexiou K, Matschke K. Pulmonary pharmacology & therapeutics. 2008 21:418-29. (WB) [PubMed:18453045]
2
Differential and correlated expressions of p16/p21/p27/p38 in mammary gland tumors of aged dogs. Kim HW, Ju JH, Shin JI, Seung BJ, Sur JH. Journal of veterinary science. 2017 December;18:479-485. (Rat) [Full Text Article] [PubMed:28927257] [PMC:PMC5746441] Related Antibodies: LS-C212.
3
Critical role for integrin-4 in the attenuation of murine acute lung injury by simvastatin. Chen W, Sammani S, Mitra S, Ma SF, Garcia JG, Jacobson JR. American journal of physiology. Lung cellular and molecular physiology. 2012 303:L279-85. [PubMed:22683568] [PMC:PMC3423831] Related Antibodies: LS-B1634.

☰ Filters
rabbit (173)
mouse (46)
No (217)
Yes (2)
Viewing 1-25 of 219 items
MAPK14 / p38 Antibody - Anti-MAPK14 / p38 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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(1) Publication(s)
Rabbit Polyclonal (IgG) to Mouse MAPK14 / p38
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl   0.1mg/ml   $425.00
MAPK14 / p38 Antibody - Anti-MAPK14 / p38 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human MAPK14 / p38
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   $485.00
MAPK14 / p38 Antibody - Anti-MAPK14 / p38 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human MAPK14 / p38
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
MAPK14 / p38 Antibody - Anti-MAPK14 / p38 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Rabbit Polyclonal (IgG) to Human MAPK14 / p38
Human
IHC, IHC-P, WB
Unconjugated
50µl   $425.00
MAPK14 / p38 Antibody - Western blot of C-6 glioma cell lysates in the presence of Anisomycin showing specific immunolabeling of the ~39k p38 protein phosphorylated at Thr180 and Tyr182 (Anisomycin). The immunolabeling is absent without Anisomycin (Control).
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(1) Publication(s)
Rabbit Polyclonal to Rat MAPK14 / p38
Chicken, Bovine, Mouse, Dog, Rat, Human
IHC, WB
Unconjugated
100µl   $375.00
MAPK14 / p38 Antibody - Immunohistochemistry analysis of paraffin-embedded human colon carcinoma, using p38 MAPK (Phospho-Tyr182) Antibody. The picture on the right is blocked with the phospho peptide.
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Rabbit Polyclonal (IgG) to Human MAPK14 / p38
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
MAPK14 / p38 Antibody - IHC of paraffin-embedded cervical cancer tissues using MAPK14 mouse monoclonal antibody with DAB staining.
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Mouse Monoclonal [clone 8G4D11] (IgG1) to Human MAPK14 / p38
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
100µg   1mg/ml   $365.00
MAPK14 / p38 Antibody - MAPK14 Antibody (Y322) western blot of Jurkat cell line and mouse kidney tissue lysates (35 ug/lane). The MAPK14 antibody detected the MAPK14 protein (arrow).
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Rabbit Polyclonal to Human MAPK14 / p38
Human
Flo, WB
Unconjugated
400µl   $325.00
MAPK14 / p38 Antibody - Western blot of Phospho-p38 (Y323) antibody
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Rabbit Polyclonal (IgG) to Human MAPK14 / p38
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
MAPK14 / p38 Antibody - Multi-blot analysis of p38 in a cell lysate from 12 human cancer cell lines using a 1:1000 dilution of MAPK14 / p38 antibody.
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Rabbit Polyclonal to Human MAPK14 / p38
Chicken, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Human, Monkey
IHC, IP, WB
Unconjugated
25µl   $235.00; 100µl   1mg/ml   $305.00
MAPK14 / p38 Antibody - Immunohistochemical analysis of p38 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Rabbit Polyclonal to Human MAPK14 / p38
Zebrafish, Rat, Mouse, Dog, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $245.00
MAPK14 / p38 Antibody - Western blot of MAPK14 / P38 antibody.
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Rabbit Polyclonal to Human MAPK14 / p38
Mouse, Rat, Human
IHC, IP, WB
Unconjugated
30µg   $245.00; 100µg   200µl   $385.00
MAPK14 / p38 Antibody - Immunofluorescence analysis of NIH-3T3 cells using MAPK14 antibody.
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Rabbit Monoclonal to Human MAPK14 / p38
Mouse, Rat, Human
IF, WB
Unconjugated
50µl   $295.00; 100µl   $385.00; 200µl   $560.00
MAPK14 / p38 Antibody - Immunohistochemical analysis of p38 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Rabbit Polyclonal to Human MAPK14 / p38
Zebrafish, Rat, Mouse, Dog, Human
IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $275.00
MAPK14 / p38 Antibody - MAPK14 Antibody (T180/Y182)immunohistochemistry of formalin-fixed and paraffin-embedded human lung carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining. This data demonstrates the use of the MAPK14 Antibody (T180/Y182) for immunohistochemistry.
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Rabbit Polyclonal to Human MAPK14 / p38
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
Select
Rabbit Polyclonal (IgG) to Human MAPK14 / p38
Mouse, Rat, Human
IHC, WB
Unconjugated
50µg   $435.00
Select
Rabbit Monoclonal (IgG) to Human MAPK14 / p38
Human
IHC, WB
Unconjugated
50µl   $425.00
Select
Rabbit Monoclonal (IgG) to Human MAPK14 / p38
Human
IHC, WB
Unconjugated
50µl   $425.00
MAPK14 / p38 Antibody
Select
Rabbit Polyclonal (IgG) to Human MAPK14 / p38
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
MAPK14 / p38 Antibody - Immunohistochemical analysis of p38 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
Rabbit Polyclonal to Human MAPK14 / p38
Zebrafish, Rat, Mouse, Dog, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
30µl   1mg/ml   $205.00; 100µl   1mg/ml   $245.00; 200µl   1mg/ml   $305.00
MAPK14 / p38 Antibody - Western blot of p38 antibody
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Rabbit Polyclonal (IgG) to Human MAPK14 / p38
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
MAPK14 / p38 Antibody - Immunohistochemical analysis of p38 (pY182) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
Rabbit Polyclonal to Human MAPK14 / p38
Zebrafish, Rat, Mouse, Dog, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $295.00
MAPK14 / p38 Antibody
Select
Rabbit Polyclonal (IgG) to Human MAPK14 / p38
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
MAPK14 / p38 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using p38 MAPK (Ab-322) antibody.
Select
Rabbit Polyclonal (IgG) to Human MAPK14 / p38
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $305.00
MAPK14 / p38 Antibody - Western blot of p38 MAPK expression in 293 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
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Rabbit Polyclonal to Human MAPK14 / p38
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
100µg   $305.00

Viewing 1-25 of 219 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).