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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MAP4K3 / GLK

mitogen-activated protein kinase kinase kinase kinase 3

GLK, a KHS protein kinase, activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of MEKK1. The protein has a structure similar to other GCK (Group I) kinases and contains an endophilin consensus-binding sequence PPRPPPPR, which has been shown to bind the SH3 domain of endophilin I in rat. GLK is activated by UV radiation and the proinflammatory cytokine tumor necrosis factor (TNF)-alpha.

Gene Name: mitogen-activated protein kinase kinase kinase kinase 3
Family/Subfamily: Protein Kinase , KHS
Synonyms: MAP4K3, MEK kinase kinase 3, RAB8IPL1, MEKKK 3, MEKKK3, GCK-like kinase, GLK, MAPKKKK3
Target Sequences: NM_003618 NP_003609.2 Q8IVH8

Filtered By: None
Target
MAP4K3 / GLK (36)
Reactivity
Human (36)
Mouse (14)
Rat (6)
Application
IHC (30)
IHC-P (5)
WB (34)
Flo (16)
ELISA (25)
ICC (1)
IF (3)
Peptide-ELISA (1)
Host
rabbit (34)
mouse (2)
Isotype
IgG (28)
IgM,k (2)
Clonality
monoclonal mc (2)
polyclonal pc (34)
Format
AP Conjugated (4)
APC Conjugated (3)
Azide-free (3)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (3)
Unconjugated (17)
Epitope
aa31-283 (8)
aa423-453 (8)
aa501-529 (8)
10-90 aa, N-terminal (1)
Gly4 (1)
aa10-59 (1)
Publications
No (36)
Showing 1-25 of 36 results

MAP4K3 / GLK Antibody (aa501-529) IHC-plus™ LS-B9106
Rabbit Polyclonal to Mouse MAP4K3 / GLK
Mouse, Human
Flo IHC IHC-P WB
Unconjugated
200µl  $425.00
Anti-MAP4K3 / GLK antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Mouse Map4k3 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The Map4k3 antibody detected the Map4k3 protein (arrow).
Anti-MAP4K3 / GLK antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Mouse Map4k3 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The Map4k3 antibody detected the Map4k3 protein (arrow).

MAP4K3 / GLK Antibody (aa31-283) LS-C164008
Rabbit Polyclonal to Human MAP4K3 / GLK
Human
Flo IHC IHC-P WB
Unconjugated
400µl  $305.00
MAP4K3 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Western blot of MAP4K3 Antibody in HepG2 cell line lysates (35 ug/lane). MAP4K3 (arrow) was detected using the purified antibody.
MAP4K3 Antibody IHC of formalin-fixed and paraffin-embedded brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Western blot of MAP4K3 Antibody in HepG2 cell line lysates (35 ug/lane). MAP4K3 (arrow) was detected using the purified antibody.

MAP4K3 / GLK Antibody LS-C164009
Mouse Monoclonal (IgM,k) to Human MAP4K3 / GLK
Human
WB
Unconjugated
100µl  $305.00
MAP4K3 western blot of A2058 cell line lysates (35 ug/lane). The MAP4K3 antibody detected the MAP4K3 protein (arrow).
MAP4K3 western blot of A2058 cell line lysates (35 ug/lane). The MAP4K3 antibody detected the MAP4K3 protein (arrow).

MAP4K3 / GLK Antibody (aa501-529) LS-C322837
Rabbit Polyclonal (IgG) to Mouse MAP4K3 / GLK
Mouse, Human
ELISA Flo IHC WB
Unconjugated
200µl 0.6mg/ml  $530.00

MAP4K3 / GLK Antibody (aa501-529, Biotin) LS-C215710
Rabbit Polyclonal (IgG) to Mouse MAP4K3 / GLK
Mouse, Human
ELISA Flo IHC WB
Biotin Conjugated
200µl  $680.00

MAP4K3 / GLK Antibody (aa501-529, FITC) LS-C215709
Rabbit Polyclonal (IgG) to Mouse MAP4K3 / GLK
Mouse, Human
ELISA Flo IHC WB
FITC Conjugated
200µl  $680.00

MAP4K3 / GLK Antibody (aa501-529, PE) LS-C215713
Rabbit Polyclonal (IgG) to Mouse MAP4K3 / GLK
Mouse, Human
ELISA Flo IHC WB
PE Conjugated
200µl 0.5mg/ml  $680.00

MAP4K3 / GLK Antibody (aa501-529, AP) LS-C215707
Rabbit Polyclonal (IgG) to Mouse MAP4K3 / GLK
Mouse, Human
ELISA Flo IHC WB
AP Conjugated
200µl  $680.00

MAP4K3 / GLK Antibody (aa501-529, APC) LS-C215708
Rabbit Polyclonal (IgG) to Mouse MAP4K3 / GLK
Mouse, Human
ELISA Flo IHC WB
APC Conjugated
200µl  $680.00

MAP4K3 / GLK Antibody (aa501-529, Azide-free, HRP) LS-C215712
Rabbit Polyclonal (IgG) to Mouse MAP4K3 / GLK
Mouse, Human
ELISA Flo IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

MAP4K3 / GLK Antibody (aa31-283) LS-C322836
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Human
ELISA Flo IHC WB
Unconjugated
200µl 0.63mg/ml  $530.00

MAP4K3 / GLK Antibody (aa31-283, Biotin) LS-C215703
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Human
ELISA Flo IHC WB
Biotin Conjugated
200µl  $680.00

MAP4K3 / GLK Antibody (aa31-283, FITC) LS-C215704
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Human
ELISA Flo IHC WB
FITC Conjugated
200µl  $680.00

MAP4K3 / GLK Antibody (aa31-283, PE) LS-C215706
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Human
ELISA Flo IHC WB
PE Conjugated
200µl 0.45mg/ml  $635.00

MAP4K3 / GLK Antibody (aa31-283, AP) LS-C215702
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Human
ELISA Flo IHC WB
AP Conjugated
200µl  $680.00

MAP4K3 / GLK Antibody (aa31-283, Azide-free, HRP) LS-C215705
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Human
ELISA Flo IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

MAP4K3 / GLK Antibody (aa31-283, APC) LS-C215701
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Human
ELISA Flo IHC WB
APC Conjugated
200µl  $680.00

MAP4K3 / GLK Antibody LS-C404333
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Mouse, Rat, Human
ELISA IHC WB
Unconjugated
20µl  $205.00; 60µl  $235.00; 120µl  $295.00; 200µl  $395.00
Immunohistochemistry of Human thyroid cancer using MAP4K3 Polyclonal Antibody at dilution of 1:30.
Western blot analysis of Mouse heart tissue, using MAP4K3 Polyclonal Antibody at dilution of 1:400.
Immunohistochemistry of Human thyroid cancer using MAP4K3 Polyclonal Antibody at dilution of 1:30.
Western blot analysis of Mouse heart tissue, using MAP4K3 Polyclonal Antibody at dilution of 1:400.

MAP4K3 / GLK Antibody LS-C668636
Rabbit Polyclonal to Human MAP4K3 / GLK
Human
ICC IF IHC IHC-P WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Immunohistochemistry - Paraffin Image
Immunofluorescence Image
Immunohistochemistry - Paraffin Image
Immunofluorescence Image

MAP4K3 / GLK Antibody (AP) LS-C349081
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Mouse, Rat, Human
IF IHC WB
AP Conjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded human liver injury tissue.
Immunofluorescence analysis of A549 cells.
Immunohistochemistry of paraffin-embedded human liver injury tissue.
Immunofluorescence analysis of A549 cells.

MAP4K3 / GLK Antibody (aa423-453) LS-C327448
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Human
ELISA IHC WB
Unconjugated
200µl 0.25mg/ml  $530.00

MAP4K3 / GLK Antibody (aa423-453, Azide-free, HRP) LS-C219518
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Human
ELISA IHC WB
HRP Conjugated, Azide-free
200µl  $680.00

MAP4K3 / GLK Antibody (aa423-453, AP) LS-C219514
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Human
ELISA IHC WB
AP Conjugated
200µl  $680.00

MAP4K3 / GLK Antibody LS-C666635
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Human
ELISA IHC WB
Unconjugated
100µg  $335.00

MAP4K3 / GLK Antibody LS-C676015
Rabbit Polyclonal (IgG) to Human MAP4K3 / GLK
Human
ELISA IHC IHC-P
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human heart tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human heart tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue at dilution 1:100
Showing 1-25 of 36 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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