MAP3K12

mitogen-activated protein kinase kinase kinase 12

MAP3K12 is a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

MAP3K12 (3)

Publications

No (3)

Tag

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (1)

Rat (1)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

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Rat MAP3K12 Protein (Recombinant His, N-Terminal) (Ile158-Ile399) - LS-G15333

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

31.1 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Human MAP3K12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81427

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

93.7 kDa

Price:

20 µg/$215

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MAP3K12 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115406

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

93.7 kDa

Price:

100 µg/$710

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