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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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We could not find product '(ID:104531)'. Here are some alternate products to this target that might be of interest to you.



MAP3K1 / MEKK1

mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase

MEKK1, a MAP3K type protein kinase, is a member of the stress-activated protein kinase (SAPK) pathways which convey pro-apoptotic signals. The protein consists of a C-terminal protein kinase domain and an extensive N-terminal domain that includes two proline-rich segments containing putative binding sites for proteins with SH3 domains, a consensus binding site for 14-3-3 proteins, two PH domains and an acid rich motif with two sites for cleavage by proapoptotic caspase cysteine proteases. MEKK1 activates MKK4/MAP2K4 and, to a lesser extent, MKK7/MAP2K7 in the SAPK cascade. MEKK1 also has been shown to activate the transcription factor CCAAT/enhancer-binding protein-beta-dependent gene expression via MEK1-ERK1/2 kinases in response to IFN-gamma. In MEKK1 (-/-) mouse embryonic stem cells the response of JNK to microtubule disruption, cold stress, hyperosmolarity and serum factors is lost or altered, and the response of ERK to hyperosmolarity and serum factors is diminished.

Gene Name: mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
Family/Subfamily: Protein Kinase , MAP3K
Synonyms: MAP3K1, MAPK/ERK kinase kinase 1, MAPKKK1, MAP/ERK kinase kinase 1, MEK kinase 1, MEKK, MEKK 1, MEKK1, SRXY6
Target Sequences: SK221D SK221P Q13233

Viewing 1-25 of 58 items
MAP3K1 / MEKK1 Antibody - MAP3K1 / MEKK1 antibody. IHC(P): Human Intestinal Cancer Tissue.
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Rabbit Polyclonal to Human MAP3K1 / MEKK1
Xenopus, Chicken, Zebrafish, Pig, Horse, Rabbit, Mouse, Guinea pig, Sheep, Bovine, Bat, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µg   0.5mg/ml   $355.00
MAP3K1 / MEKK1 Antibody - Immunohistochemical analysis of MEKK1 (pT1402) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Rabbit Polyclonal to Human MAP3K1 / MEKK1
Rabbit, Mouse, Rat, Pig, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $265.00
MAP3K1 / MEKK1 Antibody - Formalin-fixed, paraffin-embedded human thyroid carcinoma stained with MAP3K1 antibody (2F6).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone 2F6] (IgG2a,k) to Human MAP3K1 / MEKK1
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20µg   0.2mg/ml   $295.00; 100µg   0.2mg/ml   $465.00
MAP3K1 / MEKK1 Antibody - Formalin-fixed, paraffin-embedded human thyroid carcinoma stained with MAP3K1 antibody (2F6).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone 2F6] (IgG2a,k) to Human MAP3K1 / MEKK1
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free
100µg   1mg/ml   $465.00
MAP3K1 / MEKK1 Antibody - Formalin-fixed, paraffin-embedded human thyroid carcinoma stained with MAP3K1 antibody (2F6).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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Mouse Monoclonal [clone 2F6] (IgG2a,k) to Human MAP3K1 / MEKK1
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Ready-to-Use
7ml   $465.00
MAP3K1 / MEKK1 Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human MAP3K1 / MEKK1
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
100µl   0.5mg/ml   $385.00
MAP3K1 / MEKK1 Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 6-18%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human MAP3K1 / MEKK1
Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100µl   0.65mg/ml   $405.00
MAP3K1 / MEKK1 Antibody - Western blot analysis of MEKK1 expression in SHSY5Y (A); rat lung (B) whole cell lysates.
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Rabbit Polyclonal to Human MAP3K1 / MEKK1
Mouse, Rat, Human, Monkey
ICC, IF, WB
Unconjugated
30µl   1mg/ml   $205.00; 100µl   1mg/ml   $245.00; 200µl   1mg/ml   $305.00
MAP3K1 / MEKK1 Antibody - 1:100 staining human prostate tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Rabbit Polyclonal (IgG) to Human MAP3K1 / MEKK1
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
MAP3K1 / MEKK1 Antibody - Dot blot of Phospho-MAP3K1-T1400 antibody on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentration were 0.5ug per ml.
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Rabbit Polyclonal to Human MAP3K1 / MEKK1
Human
DB
Unconjugated
400µl   $325.00
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Rabbit Polyclonal (IgG) to Mouse MAP3K1 / MEKK1
Mouse
ELISA, IHC, WB
Unconjugated
200µl   $590.00
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Rabbit Polyclonal (IgG) to Mouse MAP3K1 / MEKK1
Mouse
ELISA, IHC, WB
HRP Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Mouse MAP3K1 / MEKK1
Mouse
ELISA, IHC, WB
Biotin Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Mouse MAP3K1 / MEKK1
Mouse
ELISA, IHC, WB
AP Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Mouse MAP3K1 / MEKK1
Mouse
ELISA, IHC, WB
APC Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Mouse MAP3K1 / MEKK1
Mouse
ELISA, IHC, WB
PE Conjugated
200µl   $740.00
MAP3K1 / MEKK1 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using MAP3K1 (Phospho-Thr1400) Antibody. The picture on the right is blocked with the phospho peptide.
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Rabbit Polyclonal (IgG) to Human MAP3K1 / MEKK1
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
Select
Rabbit Polyclonal (IgG) to Human MAP3K1 / MEKK1
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Rabbit Polyclonal (IgG) to Human MAP3K1 / MEKK1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
Select
Rabbit Polyclonal to Human MAP3K1 / MEKK1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg   100µl   1mg/ml   $305.00
MAP3K1 / MEKK1 Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using MAP3K1 (Phospho-Thr1402) antibody.
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Rabbit Polyclonal (IgG) to Human MAP3K1 / MEKK1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg   $305.00
MAP3K1 / MEKK1 Antibody - Mouse Map3k1 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded m.heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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Rabbit Polyclonal to Mouse MAP3K1 / MEKK1
Mouse
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
MAP3K1 / MEKK1 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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Rabbit Polyclonal to Human MAP3K1 / MEKK1
Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
MAP3K1 / MEKK1 Antibody - Peptide - + Immunofluorescence analysis of HeLa cells, using MAP3K1 antibody.
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Rabbit Polyclonal (IgG) to Human MAP3K1 / MEKK1
Mouse, Rat, Human
ELISA, IF
Unconjugated
100µg   $305.00
Select
Rabbit Polyclonal (IgG) to Mouse MAP3K1 / MEKK1
Mouse
ELISA, WB
Unconjugated
50µg   $285.00; 100µg   $385.00

Viewing 1-25 of 58 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).