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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MAP2K7 / MEK7

mitogen-activated protein kinase kinase 7

Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Essential component of the stress-activated protein kinase/c-Jun N-terminal kinase (SAP/JNK) signaling pathway. With MAP2K4/MKK4, is the one of the only known kinase to directly activate the stress-activated protein kinase/c-Jun N-terminal kinases MAPK8/JNK1, MAPK9/JNK2 and MAPK10/JNK3. MAP2K4/MKK4 and MAP2K7/MKK7 both activate the JNKs by phosphorylation, but they differ in their preference for the phosphorylation site in the Thr-Pro-Tyr motif. MAP2K4/MKK4 shows preference for phosphorylation of the Tyr residue and MAP2K7/MKK7 for the Thr residue. The monophosphorylation of JNKs on the Thr residue is sufficient to increase JNK activity indicating that MAP2K7/MKK7 is important to trigger JNK activity, while the additional phosphorylation of the Tyr residue by MAP2K4/MKK4 ensures optimal JNK activation. Has a specific role in JNK signal transduction pathway activated by proinflammatory cytokines. The MKK/JNK signaling pathway is also involved in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.

Gene Name: mitogen-activated protein kinase kinase 7
Family/Subfamily: Protein Kinase , MAP2K
Synonyms: MAP2K7, JNK kinase 2, MAP kinase kinase 7, MEK 7, Jnkk2, PRKMK7, SAPKK-4, SKK4, MAPK/ERK kinase 7, MAPKK 7, MAPKK7, SAPK kinase 4, JNK-activating kinase 2, JNKK 2, Map kinase kinase 7 beta 1, Map kinase kinase 7 gamma 2, MEK7, MKK7, SAPKK4
Target Sequences: AF013589 AAC16273.1 O14733

Viewing 1-25 of 92 items
MAP2K7 / MEK7 Antibody - Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal to Mouse MAP2K7 / MEK7
Mouse, Human
IHC, IHC-P, WB
Unconjugated
200µl   $425.00
MAP2K7 / MEK7 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Rabbit Polyclonal (IgG) to Human MAP2K7 / MEK7
Mouse, Rat, Human
IF, IHC-P, WB
Unconjugated
50µl   $425.00
MAP2K7 / MEK7 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using MAP2K7 (Phospho-Ser271) Antibody. The picture on the right is blocked with the phospho peptide.
Select
Rabbit Polyclonal (IgG) to Human MAP2K7 / MEK7
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
MAP2K7 / MEK7 Antibody - MEK7 Antibody in Immunohistochemistry (IHC)
Select
Mouse Monoclonal [clone 400000] (IgG1) to Human MAP2K7 / MEK7
Human
Flo, ICC, IF, IHC, WB
Unconjugated
100µl   $445.00
MAP2K7 / MEK7 Antibody - Detection of Human and Mouse MKK7 by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa, 293T, Jurkat, mouse TCMK-1, and mouse NIH3T3 cells. Antibodies: Affinity purified rabbit anti-MKK7 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Select
Rabbit Polyclonal (IgG) to Human MAP2K7 / MEK7
Mouse, Human
IHC, IP, WB
Unconjugated
100µl   1mg/ml   $395.00
MAP2K7 / MEK7 Antibody - IHC of paraffin-embedded lung cancer tissues using MAP2K7 mouse monoclonal antibody with DAB staining.
Select
Mouse Monoclonal [clone 4E5] (IgG1) to Human MAP2K7 / MEK7
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100µl   $365.00
MAP2K7 / MEK7 Antibody - Immunohistochemistry of paraffin-embedded mouse kidney using MAP2K7 antibody at dilution of 1:100 (400x lens).
Select
Rabbit Polyclonal (IgG) to Human MAP2K7 / MEK7
Mouse, Human
ICC, IF, IHC, IP, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
Select
Mouse Monoclonal (IgG1) to Human MAP2K7 / MEK7
Mouse, Human
ELISA, Flo, ICC, IHC, WB
Unconjugated
50µl   1mg/ml   $315.00; 100µl   1mg/ml   $375.00; 200µl   1mg/ml   $435.00
Select
Rabbit Polyclonal to Human MAP2K7 / MEK7
Human
WB
Unconjugated
10blot   $650.00
MAP2K7 / MEK7 Antibody - WB: Recombinant MKK7b1 (14-542) was left untreated (Lane 1) or phosphorylated by MEKK1 (14-196) (Lane 2) and probed with anti-phospho-MKK7/SKK4 (Thr275/Ser277) (1:1000 dilution).
Select
Rabbit Polyclonal (IgG) to Human MAP2K7 / MEK7
Human
WB
Unconjugated
100µl   $455.00
MAP2K7 / MEK7 Antibody - MEK7 antibody IHC-paraffin. IHC(P): Mouse Lung Tissue.
Select
Rabbit Polyclonal to Human MAP2K7 / MEK7
Mouse, Dog, Sheep, Rat, Pig, Bat, Human
IHC, IHC-P, WB
Unconjugated
100µg   $355.00
Select
Rabbit Polyclonal (IgG) to Mouse MAP2K7 / MEK7
Mouse, Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
Select
Mouse Monoclonal (IgG1) to Human MAP2K7 / MEK7
Mouse, Human
ELISA, IF, WB
Unconjugated
100µg   $695.00
Select
Mouse Monoclonal (IgG1) to Human MAP2K7 / MEK7
Mouse, Human
ELISA, IF, WB
HRP Conjugated
100µl   $890.00
Select
Mouse Monoclonal (IgG1) to Human MAP2K7 / MEK7
Mouse, Human
ELISA, IF, WB
FITC Conjugated
100µl   $890.00
Select
Mouse Monoclonal (IgG1) to Human MAP2K7 / MEK7
Mouse, Human
ELISA, IF, WB
AP Conjugated
100µl   $890.00
Select
Mouse Monoclonal (IgG1) to Human MAP2K7 / MEK7
Mouse, Human
ELISA, IF, WB
PE Conjugated
100µl   $890.00
Select
Mouse Monoclonal (IgG1) to Human MAP2K7 / MEK7
Mouse, Human
ELISA, IF, WB
APC Conjugated
100µl   $890.00
MAP2K7 / MEK7 Antibody
Select
Rabbit Polyclonal (IgG) to Human MAP2K7 / MEK7
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µg   $435.00
MAP2K7 / MEK7 Antibody - Immunofluorescence of monoclonal antibody to MAP2K7 on HeLa cell. [antibody concentration 10 ug/ml].
Select
Mouse Monoclonal [clone 2G5] (IgG1,k) to Human MAP2K7 / MEK7
Human
ELISA, IF, WB
Unconjugated
100µg   $365.00
Select
Rabbit Polyclonal to Human MAP2K7 / MEK7
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
200µg   $455.00
Select
Rabbit Polyclonal (IgG) to Human MAP2K7 / MEK7
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
MAP2K7 / MEK7 Antibody - Western blot of Phospho-MEK-7 (S271) antibody
Select
Rabbit Polyclonal (IgG) to Human MAP2K7 / MEK7
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
MAP2K7 / MEK7 Antibody
Select
Rabbit Polyclonal (IgG) to Human MAP2K7 / MEK7
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
MAP2K7 / MEK7 Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded humanbrain tissue using MAP2K7 (Phospho-Ser271) antibody.
Select
Rabbit Polyclonal (IgG) to Human MAP2K7 / MEK7
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µg   $305.00

Viewing 1-25 of 92 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).