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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
Protein Family And Group
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MAP2K5 / MEK5

mitogen-activated protein kinase kinase 5

MAP2K5 / MEK5 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described.

Gene Name: mitogen-activated protein kinase kinase 5
Family/Subfamily: Protein Kinase , MAP2K
Synonyms: MAP2K5, HsT17454, MAPKK 5, MEK 5, MAPKK5, MEK5, MKK5, MAP kinase kinase 5, PRKMK5, MAP kinase kinase MEK5b, MAPK/ERK kinase 5
Target Sequences: NM_145160 NP_660143.1 Q13163

☰ Filters
Viewing 1-7 of 7 items
MAP2K5 / MEK5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc + DDK
48.8 kDa
20µg   $195.00
MAP2K5 / MEK5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc + DDK
49.9 kDa
20µg   $195.00
MAP2K5 / MEK5 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue
Select
Wheat Germ Extract
GST,N-terminus
10µg   $425.00; 25µg   $590.00
MAP2K5 / MEK5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc + DDK
48.8 kDa
100µg   $485.00
MAP2K5 / MEK5 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc + DDK
49.9 kDa
100µg   $365.00
Select
Insect Cells
GST,N-terminus
Biologically active
~77 kDa
10µg   $365.00
MAP2K5 / MEK5 Protein - 12.5% SDS-PAGE of human MAP2K5 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
75.02 kDa
10µg   $425.00; 25µg   $590.00

Viewing 1-7 of 7 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).