MAP2K3 / MEK3 / MKK3

mitogen-activated protein kinase kinase 3

MAP2K3 / MEK3 / MKK3 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene.

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Proteins (9)

Type

Over-Expression Lysate (2)

Recombinant (7)

Target

MAP2K3 / MEK3 / MKK3 (9)

Publications

No (9)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (4)

Species

Human (8)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human MAP2K3 / MEK3 / MKK3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65472

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36 kDa

Price:

20 µg/$1,107

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Human MAP2K3 / MEK3 / MKK3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65474

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.1 kDa

Price:

20 µg/$1,107

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Human MAP2K3 / MEK3 / MKK3 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G59754

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human MAP2K3 / MEK3 / MKK3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75632

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.1 kDa

Price:

20 µg/$150

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Human MAP2K3 / MEK3 / MKK3 Protein (Recombinant His-T7) (aa99-343) - LS-G15356

Source:

E. coli

Tag:

His-T7

Molecular Weight:

32.1 kDa

Price:

10 µg/$277; 50 µg/$417; 100 µg/$667; 200 µg/$832; 1 mg/$1,922; 500 µg/$1,470; 5 mg/$2,913; 2 mg/$2,107

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Human MAP2K3 / MEK3 / MKK3 Protein (Recombinant His-SUMO) (Full Length) - LS-G20945

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

55.3 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human MAP2K3 / MEK3 / MKK3 Protein (Recombinant GST) (Full Length) - LS-G29925

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

63.91 kDa

Price:

2 µg/$439

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MAP2K3 / MEK3 / MKK3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102309

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.1 kDa

Price:

100 µg/$494

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Human MAP2K3 / MEK3 / MKK3 Protein (Recombinant His) - LS-G1228

Source:

E. coli

Tag:

His

Price:

10 µg/$361; 50 µg/$739

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