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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MANF / ARMET

mesencephalic astrocyte-derived neurotrophic factor

MANF / ARMET is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and results in cell proliferation. Activity of this protein is important in promoting the survival of dopaminergic neurons. The presence of polymorphisms in the N-terminal arginine-rich region, including a specific mutation that changes an ATG start codon to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus no longer thought to be tumor-related.

Gene Name: mesencephalic astrocyte-derived neurotrophic factor
Synonyms: MANF, ARP, ARMET, Arginine-rich protein, Protein ARMET
Target Sequences: NM_006010 NP_006001.4 P55145

Publications (1)

1
Piperine ameliorates SCA17 neuropathology by reducing ER stress. Guo J, Cui Y, Liu Q, Yang Y, Li Y, Weng L, Tang B, Jin P, Li XJ, Yang S, Li S. Molecular neurodegeneration. 2018 January;13:4. (Human) [Full Text Article] [PubMed:29378605] [PMC:PMC5789626] Related Antibodies: LS-B2688.

Filtered by: None
Target
MANF / ARMET (44)
Reactivity
Human (41)
Mouse (19)
Rat (14)
Bat (4)
Bovine (5)
Chicken (4)
Chimpanzee (3)
Dog (1)
Gibbon (3)
Guinea pig (4)
Hamster (1)
Horse (5)
Monkey (5)
Pig (5)
Rabbit (5)
Zebrafish (4)
Application
IHC (11)
IHC-P (3)
WB (36)
ELISA (21)
IF (5)
IP (1)
Peptide-ELISA (1)
Host
rabbit (41)
mouse (2)
goat (1)
Isotype
IgG (23)
IgG1,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (43)
Clone
1D10 (1)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (28)
Epitope
aa23-51 (8)
aa28-182 (8)
aa103-152 (4)
1-50 aa, Internal (1)
aa1-50 (1)
aa132-182 (1)
aa20-70 (1)
aa25-182 (1)
aa62-73 (1)
Publications
No (43)
Yes (1)
Showing 1-25 of 44 results

IHC-plus™ MANF / ARMET Antibody LS-B2688
Publications (1)
Publications (1)
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg 1mg/ml  $545.00
Anti-MANF / ARMET antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Immunofluorescence of MANF in Human Brain cells with MANF antibody at 20 ug/ml.

MANF / ARMET Antibody LS-C53208
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µg 1mg/ml  $365.00
Immunohistochemistry of MANF in human brain tissue with MANF antibody at 2.5 ug/ml.
Immunofluorescence of MANF in Human Brain cells with MANF antibody at 20 ug/ml.

IHC-plus™ MANF / ARMET Antibody LS-B13898
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Human
IF, IHC, IHC-P, WB
Unconjugated
50µl  $425.00
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)

MANF / ARMET Antibody (1-50 aa, Internal) LS-C387077
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Immunohistochemistry of ARP antibody
Immunohistochemistry of ARP antibody

MANF / ARMET Antibody LS-C412658
Rabbit Polyclonal to Human MANF / ARMET
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
100µl  $385.00

MANF / ARMET Antibody (aa25-182) LS-C375274
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Human
ELISA, IHC, IHC-P
Unconjugated
50µl  $285.00; 100µl  $385.00
Immunohistochemistry of paraffin-embedded human endometrial cancer using antibody at 1:100 dilution.
Immunohistochemistry of paraffin-embedded human liver using antibody at 1:100 dilution.

MANF / ARMET Antibody LS-C748423
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Human
IHC, WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Immunohistochemistry of paraffin-embedded human liver using MANF antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded human colon carcinoma using MANF antibody at dilution of 1:100 (40x lens).

MANF / ARMET Antibody LS-C767998
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Human
IF, WB
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

MANF / ARMET Antibody LS-C488221
Rabbit Polyclonal to Human MANF / ARMET
Human
ELISA, IP, WB
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

MANF / ARMET Antibody LS-C767997
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Human
IHC, WB
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

MANF / ARMET Antibody LS-C402904
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20µl 0.3mg/ml  $205.00; 60µl 0.3mg/ml  $235.00; 120µl 0.3mg/ml  $295.00; 200µl 0.3mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human colon cancer using MANF Polyclonal Antibody at dilution of 1:70.
Immunohistochemistry of paraffin-embedded Human colon cancer using MANF Polyclonal Antibody at dilution of 1:70.

MANF / ARMET Antibody LS-C406140
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20µl 0.3mg/ml  $205.00; 60µl 0.3mg/ml  $235.00; 120µl 0.3mg/ml  $295.00; 200µl 0.3mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human lung cancer using MANF Polyclonal Antibody at dilution of 1:50.
Immunohistochemistry of paraffin-embedded Human lung cancer using MANF Polyclonal Antibody at dilution of 1:50.

MANF / ARMET Antibody (clone 1D10) LS-C198507
Mouse Monoclonal [clone 1D10] (IgG1,k) to Human MANF / ARMET
Human
ELISA, WB
Unconjugated
100µg  $365.00
Detection limit for recombinant GST tagged ARMET is 0.03 ng/ml as a capture antibody.

MANF / ARMET Antibody (aa23-51) LS-C322813
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Human
ELISA, WB
Unconjugated
200µl  $590.00

MANF / ARMET Antibody (aa23-51, Biotin) LS-C262498
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Human
ELISA, WB
Biotin Conjugated
200µl  $740.00

MANF / ARMET Antibody (aa23-51, FITC) LS-C262499
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Human
ELISA, WB
FITC Conjugated
200µl  $740.00

MANF / ARMET Antibody (aa23-51, AP) LS-C262496
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Human
ELISA, WB
AP Conjugated
200µl  $740.00

MANF / ARMET Antibody (aa23-51, APC) LS-C262497
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Human
ELISA, WB
APC Conjugated
200µl  $740.00

MANF / ARMET Antibody (aa23-51, Azide-free, HRP) LS-C262500
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl  $740.00

MANF / ARMET Antibody (aa23-51, PE) LS-C262501
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Human
ELISA, WB
PE Conjugated
200µl  $740.00

MANF / ARMET Antibody LS-C743290
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Mouse, Rat, Human
ELISA, WB
Unconjugated
50µg 1mg/ml  $265.00; 100µg 1mg/ml  $325.00
Western blot analysis of lysate from 293 cells, using MANF Antibody.

MANF / ARMET Antibody LS-C803241
Rabbit Polyclonal (IgG) to Human MANF / ARMET
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Western blot Image
Western blot Image

MANF / ARMET Antibody (aa20-70) LS-C483040
Rabbit Polyclonal to Mouse MANF / ARMET
Mouse, Rat, Human
IHC
Unconjugated
100µl  $325.00
Rabbit antibody to MANF (20-70). IHC-P on paraffin sections of rat testis. The animal was perfused using Autoperfuser at a pressure of 110 mm Hg with 300 ml 4% FA and further post fixed overnight before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered through a 0.2 micron filter. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions. Primary antibody: dilution 1:1000, incubated 30 min at RT (using Autostainer). Sections were counterstained with Harris Hematoxylin.

MANF / ARMET Antibody LS-C488218
Rabbit Polyclonal to Mouse MANF / ARMET
Mouse
ELISA
Unconjugated
50µl  $275.00; 100µl  $355.00

MANF / ARMET Antibody LS-C488219
Rabbit Polyclonal to Mouse MANF / ARMET
Mouse
ELISA
Unconjugated
100µl  $255.00; 200µl  $305.00; 400µl  $355.00
Showing 1-25 of 44 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).