MANEA / ENDO

mannosidase, endo-alpha

N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005 [PubMed 15677381]).[supplied by OMIM, Sep 2008]

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

MANEA / ENDO (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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MANEA / ENDO Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109780

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.5 kDa

Price:

100 µg/$710

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Human MANEA / ENDO Protein (Recombinant GST) (Full Length) - LS-G35247

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

80.1 kDa

Price:

10 µg/$479; 25 µg/$670

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Human MANEA / ENDO Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G85104

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

53.5 kDa

Price:

20 µg/$215

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