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MALT1

mucosa associated lymphoid tissue lymphoma translocation gene 1

Enhances BCL10-induced activation of NF-kappa-B. Involved in nuclear export of BCL10. Binds to TRAF6, inducing TRAF6 oligomerization and activation of its ligase activity. Has ubiquitin ligase activity. MALT1-dependent BCL10 cleavage plays an important role in T-cell antigen receptor-induced integrin adhesion.

Gene Name: mucosa associated lymphoid tissue lymphoma translocation gene 1
Family/Subfamily: Protease , Cysteine C14
Synonyms: MALT1, Caspase-like protein, MLT, MLT1, Paracaspase, MALT associated translocation
Target Sequences: NM_006785 NP_006776.1 Q9UDY8

Publications (1)

1
Gene expression profiling of pulmonary mucosa-associated lymphoid tissue lymphoma identifies new biologic insights with potential diagnostic and therapeutic applications. Chng WJ, Remstein ED, Fonseca R, Bergsagel PL, Vrana JA, Kurtin PJ, Dogan A. Blood. 2009 113:635-45. (WB) [PubMed:18974375] [PMC:PMC2628370]

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Products
Proteins (10)
Over-Expression Lysate (4)
Recombinant (6)
MALT1 (10)
No (10)
GST, N-terminus (2)
Myc-DDK (Flag) (6)
Myc-DDK (Flag), C-terminus (1)
TRX-6His, N-terminus (1)
Human (7)
Mouse (1)
293T Cells (2)
E. coli (1)
HEK 293 Cells (5)
Wheat Germ Extract (2)
Purified (2)
MALT1 Protein - 12.5% SDS-PAGE of human MALT1 stained with Coomassie Blue
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Wheat Germ Extract
GST, N-terminus
117.5 kDa
10 µg/$479; 25 µg/$670
MALT1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MALT1 Protein - Purified recombinant protein MALT1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
92.1 kDa
20 µg/$1,107
MALT1 Protein - Purified recombinant protein MALT1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
90.9 kDa
20 µg/$1,107
MALT1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
92.1 kDa
20 µg/$215
MALT1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
90.9 kDa
20 µg/$150
MALT1 Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
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E. coli
TRX-6His, N-terminus
27 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 500 µg/$949
MALT1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
92.1 kDa
100 µg/$710
MALT1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
90.9 kDa
100 µg/$494
MALT1 Protein
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HEK 293 Cells
Myc-DDK (Flag), C-terminus
92.5 kDa
20 µg/$1,224
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).