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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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MAGOH

mago-nashi homolog, proliferation-associated (Drosophila)

Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. The EJC marks the position of the exon-exon junction in the mature mRNA for the gene expression machinery and the core components remain bound to spliced mRNAs throughout all stages of mRNA metabolism thereby influencing downstream processes including nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). The MAGOH-RBM8A heterodimer inhibits the ATPase activity of EIF4A3, thereby trapping the ATP-bound EJC core onto spliced mRNA in a stable conformation. The MAGOH-RBM8A heterodimer interacts with the EJC key regulator WIBG/PYM leading to EJC disassembly in the cytoplasm and translation enhancement of EJC-bearing spliced mRNAs by recruiting them to the ribosomal 48S preinitiation complex. Involved in the splicing modulation of BCL2L1/Bcl-X (and probably other apoptotic genes); specifically inhibits formation of proapoptotic isoforms such as Bcl-X(S); the function is different from the established EJC assembly.

Gene Name: mago-nashi homolog, proliferation-associated (Drosophila)
Synonyms: MAGOH, MAGOHA, MAGOH1, Mago nashi protein homolog, Protein mago nashi homolog
Target Sequences: NM_002370 NP_002361.1 P61326

Filtered by: None
Target
MAGOH (22)
Reactivity
Human (22)
Mouse (6)
Rat (6)
Bat (5)
Bovine (5)
Chicken (5)
Chimpanzee (3)
Dog (5)
Drosophila (5)
Gibbon (3)
Guinea pig (4)
Hamster (5)
Horse (5)
Insect (1)
Monkey (6)
Pig (5)
Rabbit (5)
Xenopus (5)
Zebrafish (5)
Application
IHC (11)
IHC-P (2)
WB (22)
ELISA (13)
IF (1)
IP (4)
Peptide-ELISA (1)
Host
rabbit (19)
mouse (2)
goat (1)
Isotype
IgG (12)
IgG1 (1)
IgG1,k (1)
Clonality
monoclonal mc (2)
polyclonal pc (20)
Clone
6E11 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (2)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (13)
Epitope
aa46-74 (8)
aa31-80 (4)
aa1-111 (1)
aa98-109 (1)
Publications
No (22)
Showing 1-22 of 22 results

MAGOH Antibody (aa46-74) LS-C163974
Rabbit Polyclonal to Human MAGOH
Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
MAGOH Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human stomach tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
MAGOH Antibody western blot of K562 cell line lysates (35 ug/lane). The MAGOH antibody detected the MAGOH protein (arrow).

MAGOH Antibody LS-C676014
Rabbit Polyclonal (IgG) to Human MAGOH
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human kidney tissue at dilution of 1:100
Immunohistochemistry of paraffin-embedded human ovarian cancer at dilution of 1:100

MAGOH Antibody LS-C802782
Rabbit Polyclonal (IgG) to Human MAGOH
Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image

MAGOH Antibody LS-C666612
Rabbit Polyclonal (IgG) to Human MAGOH
Human
ELISA, IHC, IP, WB
Unconjugated
100µg  $375.00

MAGOH Antibody (aa46-74) LS-C322805
Rabbit Polyclonal (IgG) to Human MAGOH
Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

MAGOH Antibody (aa46-74, Biotin) LS-C223130
Rabbit Polyclonal (IgG) to Human MAGOH
Human
ELISA, IHC, WB
Biotin Conjugated
200µl  $740.00

MAGOH Antibody (aa46-74, FITC) LS-C223131
Rabbit Polyclonal (IgG) to Human MAGOH
Human
ELISA, IHC, WB
FITC Conjugated
200µl  $740.00

MAGOH Antibody (aa46-74, AP) LS-C223127
Rabbit Polyclonal (IgG) to Human MAGOH
Human
ELISA, IHC, WB
AP Conjugated
200µl  $740.00

MAGOH Antibody (aa46-74, APC) LS-C223129
Rabbit Polyclonal (IgG) to Human MAGOH
Human
ELISA, IHC, WB
APC Conjugated
200µl  $740.00

MAGOH Antibody (aa46-74, Azide-free, HRP) LS-C223132
Rabbit Polyclonal (IgG) to Human MAGOH
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

MAGOH Antibody (aa46-74, PE) LS-C223133
Rabbit Polyclonal (IgG) to Human MAGOH
Human
ELISA, IHC, WB
PE Conjugated
200µl  $740.00

MAGOH Antibody LS-C676017
Rabbit Polyclonal (IgG) to Human MAGOH
Human
ELISA, IP, WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Western blot All Lanes: MAGOH antibody at 4.36 ug/ml Lane 1: Mouse kidney tissue Lane 2: A431 whole cell lysate Lane 3: Jurkat whole cell lysate Lane 4: Raji whole cell lysate Lane 5: K562 whole cell lysate Lane 6: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 18,13 kDa Observed band size: 17 kDa
Western blot All lanes: MAGOH antibody at 4.36µg/ml Lane 1: Mouse kidney tissue Lane 2: A431 whole cell lysate Lane 3: Jurkat whole cell lysate Lane 4: Raji whole cell lysate Lane 5: K562 whole cell lysate Lane 6: Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 18, 13 kDa Observed band size: 18 kDa

MAGOH Antibody (clone 6E11) LS-C139276
Mouse Monoclonal [clone 6E11] (IgG1,k) to Human MAGOH
Human
ELISA, WB
Unconjugated
100µg  $365.00
MAGOH monoclonal antibody (M01), clone 6E11. Western blot of MAGOH expression in HeLa.
Western blot of MAGOH expression in transfected 293T cell line by MAGOH monoclonal antibody (M01), clone 6E11.

MAGOH Antibody LS-C488216
Rabbit Polyclonal to Human MAGOH
Human
ELISA, IP, WB
Unconjugated
50µl  $255.00; 100µl  $305.00; 200µl  $355.00

MAGOH Antibody (aa98-109) LS-C55081
Goat Polyclonal to Human MAGOH
Xenopus, Chicken, Zebrafish, Insect, Drosophila, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100µg 0.5mg/ml  $405.00
MAGOH antibody (1 ug/ml) staining of nuclear HeLa lysate (35 ug protein/ml in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Goat Anti-MAGOH Antibody (1ug/ml) staining of nuclear HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescencence.

MAGOH Antibody (aa1-111, Azide-free) LS-C327807
Mouse Monoclonal (IgG1) to Human MAGOH
Human
WB
Unconjugated, Azide-free
100µg  $560.00

MAGOH Antibody LS-C767991
Rabbit Polyclonal (IgG) to Human MAGOH
Mouse, Rat, Human
WB
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

MAGOH Antibody LS-C668602
Rabbit Polyclonal to Human MAGOH
Human
WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Western blot Image

MAGOH Antibody (aa31-80) LS-C135763
Rabbit Polyclonal to Human MAGOH
Xenopus, Chicken, Zebrafish, Drosophila, Pig, Horse, Bat, Rat, Hamster, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $365.00
MAGOH antibody Western blot of MCF7 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

MAGOH Antibody (aa31-80, HRP) LS-C467356
Rabbit Polyclonal to Human MAGOH
Xenopus, Chicken, Zebrafish, Drosophila, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
MAGOH antibody Western blot of MCF7 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

MAGOH Antibody (aa31-80, Biotin) LS-C467353
Rabbit Polyclonal to Human MAGOH
Xenopus, Chicken, Zebrafish, Drosophila, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
MAGOH antibody Western blot of MCF7 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

MAGOH Antibody (aa31-80, FITC) LS-C467354
Rabbit Polyclonal to Human MAGOH
Xenopus, Chicken, Zebrafish, Drosophila, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
FITC Conjugated
100µl 1mg/ml  $385.00
MAGOH antibody Western blot of MCF7 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Showing 1-22 of 22 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).