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MAGI2 / AIP-1
membrane associated guanylate kinase, WW and PDZ domain containing 2
Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth.
| Gene Name: | membrane associated guanylate kinase, WW and PDZ domain containing 2 |
| Synonyms: | MAGI2, AIP1, ACVRINP1, ACVRIP1, ARIP1, AIP-1, KIAA0705, SSCAM, MAGI-2 |
| Target Sequences: | NM_012301 NP_036433.2 Q86UL8 |
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