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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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MAGEB2
melanoma antigen family B, 2
MAGEB2 is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.
| Gene Name: | melanoma antigen family B, 2 |
| Synonyms: | MAGEB2, Cancer/testis antigen 3.2, DAM6, MAGE-XP-2, MAGE-B2 antigen, Melanoma-associated antigen B2, MAGE XP-2 antigen, Melanoma antigen family B, 2, CT3.2 |
| Target Sequences: | NM_002364 NP_002355.2 O15479 |
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