MAEL

maelstrom spermatogenic transposon silencer

Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

MAEL (3)

Publications

No (3)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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MAEL Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108587

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49 kDa

Price:

100 µg/$494

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Human MAEL Protein (Recombinant GST) (Full Length) - LS-G35874

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

75.6 kDa

Price:

10 µg/$479; 25 µg/$670

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Human MAEL Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84305

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49 kDa

Price:

20 µg/$150

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