MAD2B / REV7

MAD2 mitotic arrest deficient-like 2 (yeast)

Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.

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Proteins (5)

Type

Over-Expression Lysate (4)

Recombinant (1)

Target

MAD2B / REV7 (5)

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No (5)

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Myc-DDK (Flag) (5)

Species

Human (3)

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293T Cells (2)

HEK 293 Cells (3)

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MAD2B / REV7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124599

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.2 kDa

Price:

100 µg/$494

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MAD2B / REV7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115372

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.2 kDa

Price:

100 µg/$494

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Human MAD2B / REV7 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68687

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.2 kDa

Price:

20 µg/$1,107

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Human MAD2B / REV7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82792

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.2 kDa

Price:

20 µg/$150

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Human MAD2B / REV7 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82793

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

24.2 kDa

Price:

20 µg/$150

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